RPF101

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H123112

CAS#: N/A

Description: RPF101 is a new capsaicin-like analogue. RPF101 disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast cancer cells.

Chemical Structure

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RPF101
CAS# N/A
Instruction

Theoretical Analysis

Hodoodo Cat#: H123112
Name: RPF101
CAS#: N/A
Chemical Formula: C14H13NO4S
Exact Mass: 291.06
Molecular Weight: 291.320
Elemental Analysis: C, 57.72; H, 4.50; N, 4.81; O, 21.97; S, 11.01

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: RPF101; RPF 101; RPF-101

IUPAC/Chemical Name: N-(benzo[d][1,3]dioxol-5-ylmethyl)benzenesulfonamide

InChi Key: YMEAPJBSAMZMRR-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H13NO4S/c16-20(17,12-4-2-1-3-5-12)15-9-11-6-7-13-14(8-11)19-10-18-13/h1-8,15H,9-10H2

SMILES Code: O=S(NCC1=CC=C2C(OCO2)=C1)(C3=CC=CC=C3)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 291.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: de-Sá-Júnior PL, Pasqualoto KF, Ferreira AK, Tavares MT, Damião MC, de
Azevedo RA, Câmara DA, Pereira A, de Souza DM, Parise Filho R. RPF101, a new
capsaicin-like analogue, disrupts the microtubule network accompanied by arrest
in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7
breast cancer cells. Toxicol Appl Pharmacol. 2013 Feb 1;266(3):385-98. doi:
10.1016/j.taap.2012.11.029. Epub 2012 Dec 10. PMID: 23238560.

2: Chaves OA, Tavares MT, Cunha MR, Parise-Filho R, Sant'Anna CMR, Netto-
Ferreira JC. Multi-Spectroscopic and Theoretical Analysis on the Interaction
between Human Serum Albumin and a Capsaicin Derivative-RPF101. Biomolecules.
2018 Aug 23;8(3):78. doi: 10.3390/biom8030078. PMID: 30142945; PMCID:
PMC6164054.