WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130382
CAS#: N/A
Description: Pomalidomide-benzyl-piperazine hydrochloride serves a building block in the synthesis of targeted protein degraders and PROTACs. Pomalidomide-benzyl-piperazine hydrochloride is comprised of a Cereblon (CRBN)-recruiting ligand, a rigid linker, and a pendant amine that reacts with a carboxylic acid on the target ligand.
Hodoodo Cat#: H130382
Name: Pomalidomide-benzyl-piperazine hydrochloride
CAS#: N/A
Chemical Formula: C25H26ClN5O5
Exact Mass: 0.00
Molecular Weight: 511.960
Elemental Analysis: C, 58.65; H, 5.12; Cl, 6.92; N, 13.68; O, 15.63
Synonym: Pomalidomide-benzyl-piperazine hydrochloride; Pomalidomide-benzyl-piperazine HCl
IUPAC/Chemical Name: N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-4-(piperazin-1-ylmethyl)benzamide hydrochloride
InChi Key: CJAQBVLFPMVHTH-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H25N5O5.ClH/c31-20-9-8-19(23(33)28-20)30-24(34)17-2-1-3-18(21(17)25(30)35)27-22(32)16-6-4-15(5-7-16)14-29-12-10-26-11-13-29;/h1-7,19,26H,8-14H2,(H,27,32)(H,28,31,33);1H
SMILES Code: O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)C4=CC=C(CN5CCNCC5)C=C4.[H]Cl
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 511.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |