WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H123148
CAS#: 142347-81-7
Description: tans-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker and also a alkyl chain-based PROTAC linker
Hodoodo Cat#: H123148
Name: tans-4-Hydroxy-D-proline hydrochloride
CAS#: 142347-81-7
Chemical Formula: C5H10ClNO3
Exact Mass: 167.03
Molecular Weight: 167.590
Elemental Analysis: C, 35.83; H, 6.01; Cl, 21.15; N, 8.36; O, 28.64
Synonym: 142347-81-7; trans-4-Hydroxy-D-proline hydrochloride; trans-4-Hydroxy-D-Prolinehydrochloride; TRANS-4-HYDROXY-D-PROLINE HCL; Trans-4-hydroxy-d-proline, HCl
IUPAC/Chemical Name: (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid hydrochloride
InChi Key: YEJFFQAGTXBSTI-RFKZQXLXSA-N
InChi Code: InChI=1S/C5H9NO3.ClH/c7-3-1-4(5(8)9)6-2-3;/h3-4,6-7H,1-2H2,(H,8,9);1H/t3-,4+;/m0./s1
SMILES Code: OC([C@H]1C[C@H](O)CN1)=O.Cl
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 167.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |