WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130389
CAS#: N/A
Description: CCW16-C6-BocNH is an important component of the synthesis of molecules for targeted protein degradation and the development of PROTACs. The conjugate is composed of a RING finger protein 4 (RNF4)-recruiting ligand, an alkyl-chain crosslinker, and a pendant amine that reacts with a carboxylic acid on the target ligand.
Hodoodo Cat#: H130389
Name: CCW16-C6-BocNH
CAS#: N/A
Chemical Formula: C32H39ClN2O5
Exact Mass: 566.25
Molecular Weight: 567.123
Elemental Analysis: C, 67.77; H, 6.93; Cl, 6.25; N, 4.94; O, 14.11
Synonym: CCW16-C6-BocNH
IUPAC/Chemical Name: tert-butyl (6-(4-(4-(N-benzyl-2-chloroacetamido)phenoxy)phenoxy)hexyl)carbamate
InChi Key: YTSXJHIPEILIQY-UHFFFAOYSA-N
InChi Code: InChI=1S/C32H39ClN2O5/c1-32(2,3)40-31(37)34-21-9-4-5-10-22-38-27-17-19-29(20-18-27)39-28-15-13-26(14-16-28)35(30(36)23-33)24-25-11-7-6-8-12-25/h6-8,11-20H,4-5,9-10,21-24H2,1-3H3,(H,34,37)
SMILES Code: O=C(OC(C)(C)C)NCCCCCCOC1=CC=C(OC2=CC=C(N(CC3=CC=CC=C3)C(CCl)=O)C=C2)C=C1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 567.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |