WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130400
CAS#: N/A
Description: BocA1V2PF2-NHC6-NH2 is a vital component in the synthesis of targeted protein degraders and specific and non-genetic inhibitor of apoptosis protein (IAP)-dependent protein erasers (SNIPER) technology. The conjugate is comprised of a silico-derived IAP-recruiting ligand, an alkyl-chain crosslinker, and a pendant amine for reactivity with an acid on a target warhead.
Hodoodo Cat#: H130400
Name: BocA1V2PF2-NHC6-NH2
CAS#: N/A
Chemical Formula: C36H57FN6O6
Exact Mass: 688.43
Molecular Weight: 688.886
Elemental Analysis: C, 62.77; H, 8.34; F, 2.76; N, 12.20; O, 13.93
Synonym: BocA1V2PF2-NHC6-NH2
IUPAC/Chemical Name: tert-butyl ((S)-1-(((S)-2-((S)-2-(((S)-1-((6-aminohexyl)amino)-3-(4-fluorophenyl)-1-oxopropan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)amino)-1-oxopropan-2-yl)carbamate
InChi Key: PVBBARWLUGITSU-DFZCOPKLSA-N
InChi Code: InChI=1S/C36H57FN6O6/c1-24(40-35(48)49-36(2,3)4)31(44)42-30(26-13-8-7-9-14-26)34(47)43-22-12-15-29(43)33(46)41-28(23-25-16-18-27(37)19-17-25)32(45)39-21-11-6-5-10-20-38/h16-19,24,26,28-30H,5-15,20-23,38H2,1-4H3,(H,39,45)(H,40,48)(H,41,46)(H,42,44)/t24-,28-,29-,30-/m0/s1
SMILES Code: O=C(OC(C)(C)C)N[C@@H](C)C(N[C@@H](C1CCCCC1)C(N2[C@H](C(N[C@@H](CC3=CC=C(F)C=C3)C(NCCCCCCN)=O)=O)CCC2)=O)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 688.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
