WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130455
CAS#: N/A
Description: SA7060 is a neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE) dual inhibitor, preventing (DOCA)-salt-induced hypertension and related organ damage.
Hodoodo Cat#: H130455
Name: SA7060
CAS#: N/A
Chemical Formula: C25H34N2O6
Exact Mass: 458.24
Molecular Weight: 458.560
Elemental Analysis: C, 65.48; H, 7.47; N, 6.11; O, 20.93
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: SA7060; SA 7060; SA-7060
IUPAC/Chemical Name: (S)-2-(3-((S)-3-butoxy-2-hydroxy-3-oxopropyl)-3-isobutylureido)-3-(naphthalen-2-yl)propanoic acid
InChi Key: BUMOZZPKRUULDJ-VXKWHMMOSA-N
InChi Code: InChI=1S/C25H34N2O6/c1-4-5-12-33-24(31)22(28)16-27(15-17(2)3)25(32)26-21(23(29)30)14-18-10-11-19-8-6-7-9-20(19)13-18/h6-11,13,17,21-22,28H,4-5,12,14-16H2,1-3H3,(H,26,32)(H,29,30)/t21-,22-/m0/s1
SMILES Code: O=C(O)[C@@H](NC(N(C[C@@H](C(OCCCC)=O)O)CC(C)C)=O)CC1=CC=C2C=CC=CC2=C1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 458.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Kuro T, Okahara A, Nose M, Ikuse T, Matsumura Y. Effects of SA7060, a novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme, on deoxycorticosterone acetate-salt-induced hypertension in rats. Biol Pharm Bull. 2000 Jul;23(7):820-5. doi: 10.1248/bpb.23.820. PMID: 10919359.