WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H123549
CAS#: N/A
Description: YZ-167 is a PROTAC targeting HDAC.
Hodoodo Cat#: H123549
Name: YZ167
CAS#: N/A
Chemical Formula: C33H37N5O7
Exact Mass: 615.27
Molecular Weight: 615.690
Elemental Analysis: C, 64.38; H, 6.06; N, 11.38; O, 18.19
This product is not in stock, which may be available by custom synthesis.
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Synonym: YZ167; YZ 167; YZ-167
IUPAC/Chemical Name: (E)-8-(2-(4-((5-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pent-4-yn-1-yl)oxy)benzylidene)hydrazineyl)-N-hydroxy-8-oxooctanamide
InChi Key: BNOFYYKLSQEOFU-KEIPNQJHSA-N
InChi Code: InChI=1S/C33H37N5O7/c39-29-19-18-28(32(42)35-29)38-22-27-24(10-8-11-26(27)33(38)43)9-4-3-7-20-45-25-16-14-23(15-17-25)21-34-36-30(40)12-5-1-2-6-13-31(41)37-44/h8,10-11,14-17,21,28,44H,1-3,5-7,12-13,18-20,22H2,(H,36,40)(H,37,41)(H,35,39,42)/b34-21+
SMILES Code: O=C(NC1=O)CCC1N(C2=O)CC3=C2C=CC=C3C#CCCCOC4=CC=C(/C=N/NC(CCCCCCC(NO)=O)=O)C=C4
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 615.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |