WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H123560
CAS#: N/A
Description: T5626448 is a TLR inhibitor
Hodoodo Cat#: H123560
Name: T5626448
CAS#: N/A
Chemical Formula: C19H21NO3S
Exact Mass: 343.12
Molecular Weight: 343.440
Elemental Analysis: C, 66.45; H, 6.16; N, 4.08; O, 13.98; S, 9.33
This product is not in stock, which may be available by custom synthesis.
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Synonym: T5626448; T-5626448; T 5626448
IUPAC/Chemical Name: (5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)-D-phenylalanine
InChi Key: OGDPWNWLAYZPKA-OAHLLOKOSA-N
InChi Code: InChI=1S/C19H21NO3S/c21-18(17-12-14-9-5-2-6-10-16(14)24-17)20-15(19(22)23)11-13-7-3-1-4-8-13/h1,3-4,7-8,12,15H,2,5-6,9-11H2,(H,20,21)(H,22,23)/t15-/m1/s1
SMILES Code: O=C(N[C@H](CC1=CC=CC=C1)C(O)=O)C2=CC3=C(S2)CCCCC3
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 343.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
Dela Justina V, Giachini FR, Priviero F, Webb RC. Double-stranded RNA and Toll-like receptor activation: a novel mechanism for blood pressure regulation. Clin Sci (Lond). 2020 Jan 31;134(2):303-313. doi: 10.1042/CS20190913. PMID: 31998948; PMCID: PMC7703673.