Aß Aggregation Inhibitor DS2

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Hodoodo CAT#: H130501

CAS#: Aß aggregation inhibitor DS2

Description: Aß aggregation inhibitor DS2 is an inhibitor of Aß aggregation with an IC50 value of 2.43 ± 0.05 μM.

Chemical Structure

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Aß Aggregation Inhibitor DS2
CAS# Aß aggregation inhibitor DS2
Instruction

Theoretical Analysis

Hodoodo Cat#: H130501
Name: Aß Aggregation Inhibitor DS2
CAS#: Aß aggregation inhibitor DS2
Chemical Formula: C36H41F6N9O5
Exact Mass: 793.31
Molecular Weight: 793.772
Elemental Analysis: C, 54.47; H, 5.21; F, 14.36; N, 15.88; O, 10.08

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: AB aggregation inhibitor DS2, Aß-Ag-In-DS2, Aß Ag In DS2, Aß aggregation inhibitor-DS2, AB-Ag-In-DS2, AB Ag In DS2, AB aggregation inhibitor-DS2

IUPAC/Chemical Name: Ac-(2,2-bis((2-trifluoromethylphenyl-1H-1,2,3-triazol-4-yl)methyl))Gly-Leu-Val-OMe

InChi Key: JJVWDSVIEFHRDW-FIBWVYCGSA-N

InChi Code: InChI=1S/C36H41F6N9O5/c1-20(2)15-27(31(53)44-30(21(3)4)32(54)56-6)43-33(55)34(45-22(5)52,16-23-18-50(48-46-23)28-13-9-7-11-25(28)35(37,38)39)17-24-19-51(49-47-24)29-14-10-8-12-26(29)36(40,41)42/h7-14,18-21,27,30H,15-17H2,1-6H3,(H,43,55)(H,44,53)(H,45,52)/t27-,30-/m0/s1

SMILES Code: FC(F)(F)C1=CC=CC=C1N2C=C(CC(NC(C)=O)(C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(OC)=O)=O)=O)CC3=CN(C4=C(C(F)(F)F)C=CC=C4)N=N3)N=N2

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 793.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Mann S, Kaur A, Kaur A, Priyadarshi N, Goyal B, Singhal NK, Goyal D. Triazole-Peptide Conjugate as a Modulator of Aβ-Aggregation, Metal-Mediated Aβ-Aggregation, and Cytotoxicity. ACS Chem Neurosci. 2023 May 3;14(9):1631-1645. doi: 10.1021/acschemneuro.3c00041. Epub 2023 Apr 11. PMID: 37040092.