Mpro inhibitor 737

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H130497

CAS#: 503855-51-4

Description: Mpro inhibitor 737 is a novel SARS-CoV-2 main protease fragment-like inhibitor. It has antiviral activity in vitro models.

Chemical Structure

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Mpro inhibitor 737
CAS# 503855-51-4
Instruction

Theoretical Analysis

Hodoodo Cat#: H130497
Name: Mpro inhibitor 737
CAS#: 503855-51-4
Chemical Formula: C14H10N2O2
Exact Mass: 238.07
Molecular Weight: 238.246
Elemental Analysis: C, 70.58; H, 4.23; N, 11.76; O, 13.43

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Mpro inhibitor-737, Mpro In 737, Mpro-In- 737, Mpro In-737

IUPAC/Chemical Name: 1-(Pyridin-4-ylmethyl)indoline-2,3-dione

InChi Key: HHZNAUQZNZEDNI-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H10N2O2/c17-13-11-3-1-2-4-12(11)16(14(13)18)9-10-5-7-15-8-6-10/h1-8H,9H2

SMILES Code: O=C1N(CC2=CC=NC=C2)C3=C(C=CC=C3)C1=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 238.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Saramago LC, Santana MV, Gomes BF, Dantas RF, Senger MR, Oliveira Borges PH, Ferreira VNDS, Dos Santos Rosa A, Tucci AR, Dias Miranda M, Lukacik P, Strain-Damerell C, Owen CD, Walsh MA, Ferreira SB, Silva-Junior FP. AI-Driven Discovery of SARS-CoV-2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro. J Chem Inf Model. 2023 May 8;63(9):2866-2880. doi: 10.1021/acs.jcim.3c00409. Epub 2023 Apr 14. PMID: 37058135; PMCID: PMC10124747.