WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H556339
CAS#: 1206629-08-4
Description: TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) (Free Fatty Acid Receptor) agonist
Hodoodo Cat#: H556339
Name: TUG-499
CAS#: 1206629-08-4
Chemical Formula: C16H11Cl2NO2
Exact Mass: 319.02
Molecular Weight: 320.169
Elemental Analysis: C, 60.02; H, 3.46; Cl, 22.14; N, 4.37; O, 9.99
Synonym: TUG-499; TUG 499; TUG499;
IUPAC/Chemical Name: 3-(4-((2,6-dichloropyridin-4-yl)ethynyl)phenyl)propanoic acid
InChi Key: GCWBKYDSSJIRNJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H11Cl2NO2/c17-14-9-13(10-15(18)19-14)6-5-11-1-3-12(4-2-11)7-8-16(20)21/h1-4,9-10H,7-8H2,(H,20,21)
SMILES Code: O=C(O)CCC1=CC=C(C#CC2=CC(Cl)=NC(Cl)=C2)C=C1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 320.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
Hagesaether E, Christiansen E, Due-Hansen ME, Ulven T. Mucus can change the permeation rank order of drug candidates. Int J Pharm. 2013 Aug 16;452(1-2):276-82. doi: 10.1016/j.ijpharm.2013.05.036. Epub 2013 May 23. PMID: 23707884.