WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130527
CAS#: 56932-43-5
Description: NSC-87877 disodium is a selective SHP1/SHP2 inhibitor, leading to accelerated hepatocyte proliferation, improving liver regeneration, and decreasing markers of injury following partial hepatectomy.
Hodoodo Cat#: H130527
Name: NSC-87877 disodium
CAS#: 56932-43-5
Chemical Formula: C19H11N3Na2O7S2
Exact Mass: 502.98
Molecular Weight: 503.411
Elemental Analysis: C, 45.33; H, 2.20; N, 8.35; Na, 9.13; O, 22.25; S, 12.74
This product is not in stock, which may be available by custom synthesis.
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Synonym: NSC 87877 disodium, NSC87877 disodium, NSC87877, NSC 87877, NSC-87877, NSC.87877
IUPAC/Chemical Name: Disodium 8-hydroxy-7-[(6-sulfonatonaphthalen-2-yl)diazenyl]quinoline-5-sulfonate
InChi Key: IFVGQKHFUZRWNA-ZPZFBZIMSA-L
InChi Code: InChI=1S/C19H13N3O7S2.2Na/c23-19-16(10-17(31(27,28)29)15-2-1-7-20-18(15)19)22-21-13-5-3-12-9-14(30(24,25)26)6-4-11(12)8-13;;/h1-10,23H,(H,24,25,26)(H,27,28,29);;/q;2*+1/p-2/b22-21+;;
SMILES Code: O=S(C1=C2C=CC=NC2=C(O)C(/N=N/C3=CC=C4C=C(S(=O)([O-])=O)C=CC4=C3)=C1)([O-])=O.[Na+].[Na+]
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 503.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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