Wighteone
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    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H124071

CAS#: 51225-30-0

Description: Wighteone is a compound isolated from the aerial parts of Genista ephedroides.

Chemical Structure

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Wighteone
CAS# 51225-30-0
Instruction

Theoretical Analysis

Hodoodo Cat#: H124071
Name: Wighteone
CAS#: 51225-30-0
Chemical Formula: C20H18O5
Exact Mass: 338.12
Molecular Weight: 338.360
Elemental Analysis: C, 71.00; H, 5.36; O, 23.64

Price and Availability

Size Price Availability Quantity
100mg USD 1450 2 Weeks
200mg USD 2450 2 Weeks
500mg USD 3950 2 Weeks
1g USD 5950 2 Weeks
2g USD 8950 2 Weeks
Bulk inquiry

Synonym: Wighteone; 51225-30-0; Erythrinin B; 6-Isopentenylgenistein

IUPAC/Chemical Name: 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)-4H-chromen-4-one

InChi Key: KIMDVVKVNNSHGZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H18O5/c1-11(2)3-8-14-16(22)9-17-18(19(14)23)20(24)15(10-25-17)12-4-6-13(21)7-5-12/h3-7,9-10,21-23H,8H2,1-2H3

SMILES Code: OC1=C(C2=O)C(OC=C2C3=CC=C(C=C3)O)=CC(O)=C1C/C=C(C)/C

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 338.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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1: Sun P, Qu Y, Wang Y, Wang J, Wang X, Sheng J. Wighteone exhibits an antitumor
effect against EGFR L858R/T790M mutation non-small cell lung cancer. J Cancer.
2021 May 5;12(13):3900-3908. doi: 10.7150/jca.54574. PMID: 34093797; PMCID:
PMC8176237.

2: Cao ZW, Zeng Q, Pei HJ, Ren LD, Bai HZ, Na RN. HSP90 expression and its
association with wighteone metabolite response in HER2-positive breast cancer
cells. Oncol Lett. 2016 Jun;11(6):3719-3722. doi: 10.3892/ol.2016.4488. Epub
2016 Apr 21. PMID: 27313682; PMCID: PMC4888280.

3: Liu J, Jiang W, Xia Y, Wang X, Shen G, Pang Y. Genistein-Specific G6DT Gene
for the Inducible Production of Wighteone in Lotus japonicus. Plant Cell
Physiol. 2018 Jan 1;59(1):128-141. doi: 10.1093/pcp/pcx167. PMID: 29140457.

4: Yin H, Zhao Y, Zhang Y, Zhang H, Xu L, Zou Z, Yang W, Cheng J, Zhou Y.
Genome-wide analysis of the expression profile of Saccharomyces cerevisiae in
response to treatment with the plant isoflavone, wighteone, as a potential
antifungal agent. Biotechnol Lett. 2006 Jan;28(2):99-105. doi:
10.1007/s10529-005-4954-0. PMID: 16369693.