WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H124274
CAS#: N/A
Description: MC2791 is a 1,4-DHP-based SIRT3 activator
Hodoodo Cat#: H124274
Name: MC2791
CAS#: N/A
Chemical Formula: C25H24O5
Exact Mass: 404.16
Molecular Weight: 404.460
Elemental Analysis: C, 74.24; H, 5.98; O, 19.78
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: MC2791; MC-2791; MC 2791
IUPAC/Chemical Name: diethyl 4-benzoyl-1,4-dihydro-[1,1'-biphenyl]-2,6-dicarboxylate
InChi Key: FVEGJOZENOKHSH-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H24O5/c1-3-29-24(27)20-15-19(23(26)18-13-9-6-10-14-18)16-21(25(28)30-4-2)22(20)17-11-7-5-8-12-17/h5-16,19,22H,3-4H2,1-2H3
SMILES Code: O=C(OCC)C1=CC(C(C2=CC=CC=C2)=O)C=C(C(OCC)=O)C1C3=CC=CC=C3
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 404.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Aventaggiato M, Barreca F, Vitiello L, Vespa S, Valente S, Rotili D, Mai A,
Lotti LV, Sansone L, Russo MA, Bizzarri M, Ferretti E, Tafani M. Role of SIRT3
in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells. 2023
Feb 22;12(5):691. doi: 10.3390/cells12050691. PMID: 36899828; PMCID:
PMC10000945.
2: Nobile V, Palumbo F, Lanni S, Ghisio V, Vitali A, Castagnola M, Marzano V,
Maulucci G, De Angelis C, De Spirito M, Pacini L, D'Andrea L, Ragno R, Stazi G,
Valente S, Mai A, Chiurazzi P, Genuardi M, Neri G, Tabolacci E. Altered
mitochondrial function in cells carrying a premutation or unmethylated full
mutation of the FMR1 gene. Hum Genet. 2020 Feb;139(2):227-245. doi:
10.1007/s00439-019-02104-7. Epub 2020 Jan 9. PMID: 31919630.