WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H124739
CAS#: 98991-32-3
Description: CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor.
Hodoodo Cat#: H124739
Name: CHBO4
CAS#: 98991-32-3
Chemical Formula: C15H10BrFO
Exact Mass: 303.99
Molecular Weight: 305.150
Elemental Analysis: C, 59.04; H, 3.30; Br, 26.19; F, 6.23; O, 5.24
Synonym: CHBO4; CHBO-4; CHBO 4
IUPAC/Chemical Name: (E)-1-(4-bromophenyl)-3-(4-fluorophenyl)prop-2-en-1-one
InChi Key: JLKQXQSMJJGERH-XCVCLJGOSA-N
InChi Code: InChI=1S/C15H10BrFO/c16-13-6-4-12(5-7-13)15(18)10-3-11-1-8-14(17)9-2-11/h1-10H/b10-3+
SMILES Code: BrC1=CC=C(C(/C=C/C2=CC=C(F)C=C2)=O)C=C1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 305.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
Thomas Parambi DG, Oh JM, Kumar S, Sudevan ST, Hendawy OM, Abdelgawad MA, Musa A, Al-Sanea MM, Ahmad I, Patel H, Kim H, Mathew B. Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study. Comput Biol Chem. 2023 Aug;105:107899. doi: 10.1016/j.compbiolchem.2023.107899. Epub 2023 Jun 1. PMID: 37315342.