WES-1
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    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H124738

CAS#: 2748673-86-9

Description: WES-1 (Compound 8g) is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM).

Chemical Structure

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WES-1
CAS# 2748673-86-9
Instruction

Theoretical Analysis

Hodoodo Cat#: H124738
Name: WES-1
CAS#: 2748673-86-9
Chemical Formula: C20H20N4O3S
Exact Mass: 396.13
Molecular Weight: 396.470
Elemental Analysis: C, 60.59; H, 5.08; N, 14.13; O, 12.11; S, 8.09

Price and Availability

Size Price Availability Quantity
100mg USD 950 2 Weeks
200mg USD 1650 2 Weeks
500mg USD 3650 2 Weeks
1g USD 4650 2 Weeks
2g USD 7650 2 Weeks
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Synonym: WES-1; WES1; WES 1

IUPAC/Chemical Name: 2-(3-(2-methyl-6-(p-tolyl)pyridin-3-yl)ureido)benzenesulfonamide

InChi Key: BHEXZFRNIHDPAK-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H20N4O3S/c1-13-7-9-15(10-8-13)17-12-11-16(14(2)22-17)23-20(25)24-18-5-3-4-6-19(18)28(21,26)27/h3-12H,1-2H3,(H2,21,26,27)(H2,23,24,25)

SMILES Code: O=C(NC1=C(S(=O)(N)=O)C=CC=C1)NC2=CC=C(C3=CC=C(C)C=C3)N=C2C

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 396.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Abdel-Megied AM, Eldehna WM, Abdelrahman MA, Elbarbry FA. Development and Validation of High-Throughput Bioanalytical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for the Quantification of Newly Synthesized Antitumor Carbonic Anhydrase Inhibitors in Human Plasma. Molecules. 2020 Dec 6;25(23):5753. doi: 10.3390/molecules25235753. PMID: 33291270; PMCID: PMC7730089.