WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H124854
Description: ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases.
Hodoodo Cat#: H124854
Chemical Formula: C21H14F3N3O
Exact Mass: 381.11
Molecular Weight: 381.36
Elemental Analysis: C, 66.14; H, 3.70; F, 14.95; N, 11.02; O, 4.20
Synonym: ND-011992; ND011992; ND 011992
IUPAC/Chemical Name: N-(4-(4-(trifluoromethyl)phenoxy)phenyl)quinazolin-4-amine
InChi Key: CAIODVXPWNFDFE-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H14F3N3O/c22-21(23,24)14-5-9-16(10-6-14)28-17-11-7-15(8-12-17)27-20-18-3-1-2-4-19(18)25-13-26-20/h1-13H,(H,25,26,27)
SMILES Code: FC(F)(F)C(C=C1)=CC=C1OC(C=C2)=CC=C2NC3=NC=NC4=CC=CC=C43
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 381.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
Kägi J, Sloan W, Schimpf J, Nasiri HR, Lashley D, Friedrich T. Exploring ND-011992, a quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. Sci Rep. 2023 Jul 28;13(1):12226. doi: 10.1038/s41598-023-39430-w. PMID: 37507428; PMCID: PMC10382516.