WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H124858
CAS#: 1005057-81-7
Description: WAY-299359 is a FLT3 inhibitor
Hodoodo Cat#: H124858
Name: WAY-299359
CAS#: 1005057-81-7
Chemical Formula: C14H18N2O3S
Exact Mass: 294.10
Molecular Weight: 294.370
Elemental Analysis: C, 57.12; H, 6.16; N, 9.52; O, 16.31; S, 10.89
Synonym: WAY-299359; WAY 299359; WAY299359
IUPAC/Chemical Name: N-(3-carbamoyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)tetrahydrofuran-2-carboxamide
InChi Key: LCHVRVJNBNSFHV-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H18N2O3S/c15-12(17)11-8-4-1-2-6-10(8)20-14(11)16-13(18)9-5-3-7-19-9/h9H,1-7H2,(H2,15,17)(H,16,18)
SMILES Code: C1CCC2=C(C1)C(=C(S2)NC(=O)C3CCCO3)C(=O)N
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 294.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
Wang X, Heinz BA, Qian YW, Carter JH, Gadski RA, Beavers LS, Little SP, Yang CR, Beck JP, Hao J, Schaus JM, Svensson KA, Bruns RF. Intracellular Binding Site for a Positive Allosteric Modulator of the Dopamine D1 Receptor. Mol Pharmacol. 2018 Oct;94(4):1232-1245. doi: 10.1124/mol.118.112649. Epub 2018 Aug 15. PMID: 30111649.