WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H124916
CAS#: 2639775-01-0
Description: AMX12006 is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4 (IC50 = 4.3 nM).
Hodoodo Cat#: H124916
Name: AMX12006
CAS#: 2639775-01-0
Chemical Formula: C26H22F3N3O3
Exact Mass: 481.16
Molecular Weight: 481.480
Elemental Analysis: C, 64.86; H, 4.61; F, 11.84; N, 8.73; O, 9.97
Synonym: AMX12006; AMX-12006; AMX 12006
IUPAC/Chemical Name: 4-[(1S)-1-[[[1-methyl-3-[[3-(trifluoromethyl)phenyl]amino]-1H-indol-2-yl]carbonyl]amino]ethyl]-benzoic acid
InChi Key: BBJLZNHEYIHTCB-HNNXBMFYSA-N
InChi Code: InChI=1S/C26H22F3N3O3/c1-15(16-10-12-17(13-11-16)25(34)35)30-24(33)23-22(20-8-3-4-9-21(20)32(23)2)31-19-7-5-6-18(14-19)26(27,28)29/h3-15,31H,1-2H3,(H,30,33)(H,34,35)/t15-/m0/s1
SMILES Code: O=C(O)C1=CC=C([C@@H](NC(C(N2C)=C(NC3=CC=CC(C(F)(F)F)=C3)C4=C2C=CC=C4)=O)C)C=C1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 481.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |