WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H124909
CAS#: 2922824-09-5
Description: C18 is a covalent inhibitor of glutathione peroxidase 4 (GPX4; IC50 = 120 nM)
Hodoodo Cat#: H124909
Name: C18
CAS#: 2922824-09-5
Chemical Formula: C18H17ClFNO5
Exact Mass: 381.08
Molecular Weight: 381.780
Elemental Analysis: C, 56.63; H, 4.49; Cl, 9.29; F, 4.98; N, 3.67; O, 20.95
Synonym: C18; C 18; C-18
IUPAC/Chemical Name: 2-chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-(4-fluoro-3,5-dimethoxyphenyl)-acetamide
InChi Key: HKXSBJJCHBFTMB-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H17ClFNO5/c1-23-15-8-12(9-16(24-2)18(15)20)21(17(22)10-19)11-3-4-13-14(7-11)26-6-5-25-13/h3-4,7-9H,5-6,10H2,1-2H3
SMILES Code: O=C(N(C1=CC=C(OCCO2)C2=C1)C3=CC(OC)=C(F)C(OC)=C3)CCl
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 381.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
