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Hi 76-0079
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WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H125050

CAS#: 374567-94-9

Description: Hi 76-0079 is a hormone-sensitive lipase (HSL) inhibitor

Chemical Structure

Hi 76-0079

CAS# 374567-94-9

Instruction

Theoretical Analysis

Hodoodo Cat#: H125050
Name: Hi 76-0079
CAS#: 374567-94-9
Chemical Formula: C11H13ClN2O3
Exact Mass: 256.06
Molecular Weight: 256.690
Elemental Analysis: C, 51.47; H, 5.11; Cl, 13.81; N, 10.91; O, 18.70

Price and Availability

Size	Price	Availability
50mg	USD 450	2 Weeks
100mg	USD 750	2 Weeks
200mg	USD 1250	2 Weeks
500mg	USD 2650	2 Weeks
1g	USD 3650	2 Weeks
2g	USD 5950	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. Hodoodo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: 374567-94-9; Hi 760079; Hi76-0079; Hi-76-0079; NNC0076-0079; 76-0079

IUPAC/Chemical Name: 4-chlorophenyl morpholinocarbamate

InChi Key: CJKVBAQMCNYASH-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H13ClN2O3/c12-9-1-3-10(4-2-9)17-11(15)13-14-5-7-16-8-6-14/h1-4H,5-8H2,(H,13,15)

SMILES Code: O=C(NN1CCOCC1)OC2=CC=C(C=C2)Cl

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 256.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Lasa A, Schweiger M, Kotzbeck P, Churruca I, Simón E, Zechner R, Portillo MP.
Resveratrol regulates lipolysis via adipose triglyceride lipase. J Nutr Biochem.
2012 Apr;23(4):379-84. doi: 10.1016/j.jnutbio.2010.12.014. Epub 2011 May 2.
PMID: 21543206.

2: Sakai K, Igarashi M, Yamamuro D, Ohshiro T, Nagashima S, Takahashi M,
Enkhtuvshin B, Sekiya M, Okazaki H, Osuga J, Ishibashi S. Critical role of
neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine
macrophages. J Lipid Res. 2014 Oct;55(10):2033-40. doi: 10.1194/jlr.M047787.
Epub 2014 May 27. PMID: 24868095; PMCID: PMC4173996.

3: Wagner C, Hois V, Pajed L, Pusch LM, Wolinski H, Trauner M, Zimmermann R,
Taschler U, Lass A. Lysosomal acid lipase is the major acid retinyl ester
hydrolase in cultured human hepatic stellate cells but not essential for retinyl
ester degradation. Biochim Biophys Acta Mol Cell Biol Lipids. 2020
Aug;1865(8):158730. doi: 10.1016/j.bbalip.2020.158730. Epub 2020 May 1. PMID:
32361002; PMCID: PMC7279957.

4: Alsted TJ, Nybo L, Schweiger M, Fledelius C, Jacobsen P, Zimmermann R,
Zechner R, Kiens B. Adipose triglyceride lipase in human skeletal muscle is
upregulated by exercise training. Am J Physiol Endocrinol Metab. 2009
Mar;296(3):E445-53. doi: 10.1152/ajpendo.90912.2008. Epub 2008 Dec 23. PMID:
19106247.

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Hi 76-0079 featured