SSR-182289A (Free)

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H530209

CAS#: 363151-21-7

Description: SSR-182289A (Free) is a thrombin inhibitor potentially for the treatment of thrombosis. SSR-182289A had been in phase II clinical trials by Sanofi for the treatment of thrombosis. But, this research was discontinued in 2009.

Chemical Structure

img
SSR-182289A (Free)
CAS# 363151-21-7
Instruction

Theoretical Analysis

Hodoodo Cat#: H530209
Name: SSR-182289A (Free)
CAS#: 363151-21-7
Chemical Formula: C30H34ClF2N5O4S
Exact Mass: 633.20
Molecular Weight: 634.140
Elemental Analysis: C, 56.82; H, 5.40; Cl, 5.59; F, 5.99; N, 11.04; O, 10.09; S, 5.06

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: SSR-182289A; SSR-182289; SSR182289A; SSR182289; SSR 182289A; SSR 182289

IUPAC/Chemical Name: N-[3-[N-[4-(5-Aminopyridin-2-yl)-1(S)-[4-(difluoromethylene)piperidin-1-ylcarbonyl]butyl]sulfamoyl]biphenyl-2-yl]acetamide hydrochloride

InChi Key: JOWCHVSUAJPEIA-SNYZSRNZSA-N

InChi Code: InChI=1S/C30H33F2N5O4S.ClH/c1-20(38)35-28-25(21-7-3-2-4-8-21)10-6-12-27(28)42(40,41)36-26(11-5-9-24-14-13-23(33)19-34-24)30(39)37-17-15-22(16-18-37)29(31)32;/h2-4,6-8,10,12-14,19,26,36H,5,9,11,15-18,33H2,1H3,(H,35,38);1H/t26-;/m0./s1

SMILES Code: CC(NC1=C(S(=O)(N[C@H](C(N2CC/C(CC2)=C(F)/F)=O)CCCC3=NC=C(N)C=C3)=O)C=CC=C1C4=CC=CC=C4)=O.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: Related CAS # 362615-85-8 (HCl)

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 634.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: A role for thrombin in liver fibrosis J Gillibert Duplantier, L Dubuisson, N Senant, G Freyburger, I Laurendeau, J-M Herbert, A Desmoulière, J Rosenbaum Gut. 2004 Nov; 53(11): 1682–1687. doi: 10.1136/gut.2003.032136 PMCID: PMC1774287