WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H531478
CAS#: 885038-66-4
Description: AS1907417 is a novel GPR119 agonist.
Hodoodo Cat#: H531478
Name: AS1907417
CAS#: 885038-66-4
Chemical Formula: C19H27N3O4S
Exact Mass: 393.17
Molecular Weight: 393.502
Elemental Analysis: C, 57.99; H, 6.92; N, 10.68; O, 16.26; S, 8.15
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Synonym: AS1907417; AS-1907417; AS 1907417
IUPAC/Chemical Name: 4-[1-(2-cyclobutyl-6,6-dioxo-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl)piperidin-4-yl]butanoic acid
InChi Key: NFFANIJTECFGGM-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H27N3O4S/c23-17(24)6-1-3-13-7-9-22(10-8-13)19-15-11-27(25,26)12-16(15)20-18(21-19)14-4-2-5-14/h13-14H,1-12H2,(H,23,24)
SMILES Code: O=C(O)CCCC1CCN(C2=C3C(CS(C3)(=O)=O)=NC(C4CCC4)=N2)CC1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 393.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Yoshida S, Tanaka H, Oshima H, Yamazaki T, Yonetoku Y, Ohishi T, Matsui T, Shibasaki M. AS1907417, a novel GPR119 agonist, as an insulinotropic and β-cell preservative agent for the treatment of type 2 diabetes. Biochem Biophys Res Commun. 2010 Oct 1;400(4):745-51. doi: 10.1016/j.bbrc.2010.08.141. PubMed PMID: 20816753.