UCM 793

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H532867

CAS#: 101374-18-9

Description: UCM 793 is a non-selective MT1/MT2 receptor agonist.

Chemical Structure

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UCM 793
CAS# 101374-18-9
Instruction

Theoretical Analysis

Hodoodo Cat#: H532867
Name: UCM 793
CAS#: 101374-18-9
Chemical Formula: C12H18N2O2
Exact Mass: 222.14
Molecular Weight: 222.290
Elemental Analysis: C, 64.84; H, 8.16; N, 12.60; O, 14.39

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: UCM 793, UCM793, UCM-793

IUPAC/Chemical Name: N-[2-[(3-methoxyphenyl)-methylamino]ethyl]acetamide

InChi Key: FAWOXVGCBAVSFR-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H18N2O2/c1-10(15)13-7-8-14(2)11-5-4-6-12(9-11)16-3/h4-6,9H,7-8H2,1-3H3,(H,13,15)

SMILES Code: CC(NCCN(C1=CC=CC(OC)=C1)C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 222.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Elisi GM, Bedini A, Scalvini L, Carmi C, Bartolucci S, Lucini V, Scaglione F, Mor M, Rivara S, Spadoni G. Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria. Molecules. 2020 Sep 4;25(18):4057. doi: 10.3390/molecules25184057. PMID: 32899888; PMCID: PMC7570888.


2: Ochoa-Sanchez R, Comai S, Spadoni G, Bedini A, Tarzia G, Gobbi G. Melatonin, selective and non-selective MT1/MT2 receptors agonists: differential effects on the 24-h vigilance states. Neurosci Lett. 2014 Feb 21;561:156-61. doi: 10.1016/j.neulet.2013.12.069. Epub 2014 Jan 7. PMID: 24406151.


3: Spadoni G, Bedini A, Orlando P, Lucarini S, Tarzia G, Mor M, Rivara S, Lucini V, Pannacci M, Scaglione F. Bivalent ligand approach on N-{2-[(3-methoxyphenyl)methylamino]ethyl}acetamide: synthesis, binding affinity and intrinsic activity for MT(1) and MT(2) melatonin receptors. Bioorg Med Chem. 2011 Aug 15;19(16):4910-6. doi: 10.1016/j.bmc.2011.06.063. Epub 2011 Jun 28. PMID: 21775151.