WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H561417
CAS#: 58493-49-5
Description: Olvanil is a TRPV1 receptor agonist. Olvanil is also a capsaicin analog, but it is non-noxious and lacks capsaicin's pungency and CGRP release potential.
Hodoodo Cat#: H561417
Name: Olvanil
CAS#: 58493-49-5
Chemical Formula: C26H43NO3
Exact Mass: 417.32
Molecular Weight: 417.634
Elemental Analysis: C, 74.78; H, 10.38; N, 3.35; O, 11.49
Synonym: Olvanil; Vanillyloleamide; Olvanilo; Olvanilum;
IUPAC/Chemical Name: (Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]octadec-9-enamide
InChi Key: OPZKBPQVWDSATI-KHPPLWFESA-N
InChi Code: InChI=1S/C26H43NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)27-22-23-19-20-24(28)25(21-23)30-2/h10-11,19-21,28H,3-9,12-18,22H2,1-2H3,(H,27,29)/b11-10-
SMILES Code: CCCCCCCC/C=C\CCCCCCCC(NCC1=CC=C(O)C(OC)=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
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The following data is based on the product molecular weight 417.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Rudd JA, Nalivaiko E, Matsuki N, Wan C, Andrews PL. The involvement of TRPV1 in emesis and anti-emesis. Temperature (Austin). 2015 May 21;2(2):258-76. doi: 10.1080/23328940.2015.1043042. eCollection 2015 Apr-Jun. Review. PubMed PMID: 27227028; PubMed Central PMCID: PMC4843889.
2: Szallasi A, Di Marzo V. New perspectives on enigmatic vanilloid receptors. Trends Neurosci. 2000 Oct;23(10):491-7. Review. PubMed PMID: 11006466.
3: Di Marzo V, Melck D, De Petrocellis L, Bisogno T. Cannabimimetic fatty acid derivatives in cancer and inflammation. Prostaglandins Other Lipid Mediat. 2000 Apr;61(1-2):43-61. Review. PubMed PMID: 10785541.
4: Dray A. Neuropharmacological mechanisms of capsaicin and related substances. Biochem Pharmacol. 1992 Aug 18;44(4):611-5. Review. PubMed PMID: 1380811.
5: Dray A. Mechanism of action of capsaicin-like molecules on sensory neurons. Life Sci. 1992;51(23):1759-65. Review. PubMed PMID: 1331641.
