WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H526489
CAS#: 94212-33-6
Description: BC12-4 is a novel potent inhibitor of IL-2 secretion, demonstrating potent immunomodulatory activity.
Hodoodo Cat#: H526489
Name: BC12-4
CAS#: 94212-33-6
Chemical Formula: C19H14N2O3
Exact Mass: 318.10
Molecular Weight: 318.330
Elemental Analysis: C, 71.69; H, 4.43; N, 8.80; O, 15.08
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Synonym: BC12-4
IUPAC/Chemical Name: 1-Phenyl-5-(3-phenyl-2-propen-1-ylidene)-2,4,6(1H,3H,5H)-pyrimidinetrione
InChi Key: COXDMRSXWPMFJU-NJKRNUQASA-N
InChi Code: InChI=1S/C19H14N2O3/c22-17-16(13-7-10-14-8-3-1-4-9-14)18(23)21(19(24)20-17)15-11-5-2-6-12-15/h1-13H,(H,20,22,24)/b10-7+,16-13+
SMILES Code: O=C1NC(/C(C(N1C2=CC=CC=C2)=O)=C\C=C\C3=CC=CC=C3)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 318.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Xu C, Wyman AR, Alaamery MA, Argueta SA, Ivey FD, Meyers JA, Lerner A, Burdo TH, Connolly T, Hoffman CS, Chiles TC. Anti-inflammatory effects of novel barbituric acid derivatives in T lymphocytes. Int Immunopharmacol. 2016 Sep;38:223-32. doi: 10.1016/j.intimp.2016.06.004. Epub 2016 Jun 13. PubMed PMID: 27302770.
2: Khadse SV, Bajaj G, Vibhakar P, Nainani P, Ahuja R, Deep G. Evaluation of Specificity and Sensitivity of Oral Fluid for Diagnosis of Hepatitis B. J Clin Diagn Res. 2016 Jan;10(1):BC12-4. doi: 10.7860/JCDR/2016/17319.7107. Epub 2016 Jan 1. PubMed PMID: 26894057; PubMed Central PMCID: PMC4740584.