WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H620114
CAS#: 1808990-66-0
Description: Biotin-PEG6-Maleimide is a PEG derivative containing a biotin group and a maleimide group for labeling and crosslinking cysteines and other sulfhydryls. The maleimide group reacts specifically with sulfhydryl groups (at pH 6.5-7.5) to form a stable, irreversible thioether linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
Hodoodo Cat#: H620114
Name: Biotin-PEG6-Maleimide
CAS#: 1808990-66-0
Chemical Formula: C31H51N5O11S
Exact Mass: 701.33
Molecular Weight: 701.833
Elemental Analysis: C, 53.05; H, 7.32; N, 9.98; O, 25.08; S, 4.57
Synonym: Biotin-PEG6-Maleimide; Biotin-PEG6-Mal; Biotin Functionalized, Biotin-PEG-Maleimide, Heterobifunctional PEGs, Maleimide Functionalized, Maleimide-PEG-Biotin,
IUPAC/Chemical Name: N-[2-[2-[2-[2-[2-[2-[2-[(3-Maleimidopropionyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]biotinamide
InChi Key: ILVNKONXZBFCPD-QRQMUESOSA-N
InChi Code: InChI=1S/C31H51N5O11S/c37-26(4-2-1-3-25-30-24(23-48-25)34-31(41)35-30)32-8-11-42-13-15-44-17-19-46-21-22-47-20-18-45-16-14-43-12-9-33-27(38)7-10-36-28(39)5-6-29(36)40/h5-6,24-25,30H,1-4,7-23H2,(H,32,37)(H,33,38)(H2,34,35,41)/t24-,25-,30-/m0/s1
SMILES Code: O=C1N[C@@]([H])([C@]([H])(CS2)N1)[C@@H]2CCCCC(NCCOCCOCCOCCOCCOCCOCCNC(CCN3C(C=CC3=O)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 701.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
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In vivo protocol: |