WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H527037
CAS#: 1781835-13-9
Description: RN-1 dihydrochloride is a novel potent and selective LSD1 inhibitor and irreversible KDM1A inhibitor.
Hodoodo Cat#: H527037
Name: RN-1 dihydrochloride
CAS#: 1781835-13-9
Chemical Formula: C23H31Cl2N3O2
Exact Mass: 0.00
Molecular Weight: 452.420
Elemental Analysis: C, 61.06; H, 6.91; Cl, 15.67; N, 9.29; O, 7.07
Synonym: RN1 hydrochloride, RN-1 hydrochloride, RN1 2HCl, RN1 HCl, RN-1 2HCl, RN-1 HCl, RN1 dihydrochloride, LSD1 Inhibitor IV, LSD1 Inhibitor 4, LSD1 In IV, LSD1 In 4
IUPAC/Chemical Name: 2-(((trans)-2-(4-(Benzyloxy)phenyl)cyclopropyl)amino)-1-(4-methylpiperazin-1-yl)ethanone Dihydrochloride
InChi Key: WMHAFZOOUBPQRX-VSIGASKDSA-N
InChi Code: InChI=1S/C23H29N3O2.2ClH/c1-25-11-13-26(14-12-25)23(27)16-24-22-15-21(22)19-7-9-20(10-8-19)28-17-18-5-3-2-4-6-18;;/h2-10,21-22,24H,11-17H2,1H3;2*1H/t21-,22+;;/m0../s1
SMILES Code: CN1CCN(C(CN[C@H]2[C@H](C3=CC=C(OCC4=CC=CC=C4)C=C3)C2)=O)CC1.[H]Cl.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 452.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |