WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H527467
CAS#: 127390-77-6
Description: UCB-11056 is a modulator of cyclic AMP generation, amplifing induced cyclic AMP formation in rat brain tissue; Nootropic.
Hodoodo Cat#: H527467
Name: UCB-11056
CAS#: 127390-77-6
Chemical Formula: C12H21N5O2
Exact Mass: 267.17
Molecular Weight: 267.333
Elemental Analysis: C, 53.91; H, 7.92; N, 26.20; O, 11.97
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Synonym: UCB11056; UCB 11056; UCB-11056
IUPAC/Chemical Name: 2-((4-(4-Morpholinyl)-6-propyl-1,3,5-triazin-2-yl)amino)-ethanol
InChi Key: NERMEVBNTXXDNG-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H21N5O2/c1-2-3-10-14-11(13-4-7-18)16-12(15-10)17-5-8-19-9-6-17/h18H,2-9H2,1H3,(H,13,14,15,16)
SMILES Code: CCCC1=NC(NCCO)=NC(N2CCOCC2)=N1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 267.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Timmermans J, Amighi K, Puigdevall J, Baltes E, Moës AJ. Peroral sustained-release film-coated pellets as a means to overcome physicochemical and biological drug-related problems. II. Bioavailability and tolerance assessment in dogs. Drug Dev Ind Pharm. 1998 Jun;24(6):517-25. PubMed PMID: 9876617.
2: Amighi K, Timmermans J, Puigdevall J, Baltes E, Moës AJ. Peroral sustained-release film-coated pellets as a means to overcome physicochemical and biological drug-related problems. I. In vitro development and evaluation. Drug Dev Ind Pharm. 1998 Jun;24(6):509-15. PubMed PMID: 9876616.
3: el Tamer A, Raikoff K, Corey J, Wülfert E, Hanin I. ucb 11056, a new potential nootropic drug, amplifies induced cyclic AMP formation in rat brain tissue. J Neurochem. 1993 Dec;61(6):2256-61. PubMed PMID: 8245976.