WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H584187
CAS#: 111317-77-2
Description: BI-L 45XX is an anti inflammatory benzimidazole derivative with inhibitory effects on neutrophil function
Hodoodo Cat#: H584187
Name: BI-L 45XX
CAS#: 111317-77-2
Chemical Formula: C10H9F3N2O2S
Exact Mass: 278.03
Molecular Weight: 278.249
Elemental Analysis: C, 43.17; H, 3.26; F, 20.48; N, 10.07; O, 11.50; S, 11.52
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Synonym: BI-L 45XX; BI-L-45 XX; BI L 45 XX; BIL45XX
IUPAC/Chemical Name: 5-methyl-1-(2,2,2-trifluoroethylsulfonyl)benzimidazole
InChi Key: FKDKLZUSHUTJRL-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H9F3N2O2S/c1-7-2-3-9-8(4-7)14-6-15(9)18(16,17)5-10(11,12)13/h2-4,6H,5H2,1H3
SMILES Code: O=S(N1C2=CC=C(C)C=C2N=C1)(CC(F)(F)F)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 278.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Lazer ES, Farina PR, Oliver JT, Possanza GJ, Matteo MR. Antiinflammatory benzimidazole derivative with inhibitory effects on neutrophil function. Agents Actions. 1987 Aug;21(3-4):257-9. PubMed PMID: 3687578.