WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H584239
CAS#: 120908-94-3
Description: BN 52115 is a platelet activating factor antagonist that has been found to inhibit in vivo bronchopulmonary alteration.
Hodoodo Cat#: H584239
Name: BN 52115
CAS#: 120908-94-3
Chemical Formula: C37H60BrNO4
Exact Mass: 661.37
Molecular Weight: 662.794
Elemental Analysis: C, 67.05; H, 9.13; Br, 12.06; N, 2.11; O, 9.66
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Synonym: BN 52115; BN-52115; BN52115
IUPAC/Chemical Name: Quinolinium, 1-(6-((2-heptadecyl-2-methyl-1,3-dioxolan-4-yl)methoxy)-6-oxohexyl)-, bromide
InChi Key: FTFOSFBACGPTIP-UHFFFAOYSA-M
InChi Code: InChI=1S/C37H60NO4.BrH/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21-28-37(2)41-32-34(42-37)31-40-36(39)27-18-17-22-29-38-30-23-25-33-24-19-20-26-35(33)38;/h19-20,23-26,30,34H,3-18,21-22,27-29,31-32H2,1-2H3;1H/q+1;/p-1
SMILES Code: O=C(OCC1OC(C)(CCCCCCCCCCCCCCCCC)OC1)CCCCC[N+]2=C3C=CC=CC3=CC=C2.[Br-]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 662.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Pons F, Touvay C, Lejeune V, Carré C, Vilain B, Broquet C, Mencia-Huerta JM, Braquet P. Action of platelet-activating factor (PAF) antagonists on the bronchopulmonary effects of PAF in the guinea-pig. J Lipid Mediat. 1989 Nov-Dec;1(6):329-40. PubMed PMID: 2519901.
2: Miller LG, Bazan NG, Roy RB, Clostre F, Gaver A, Braquet P. Platelet activating factor antagonists interact with GABAA receptors. Res Commun Chem Pathol Pharmacol. 1991 Nov;74(2):253-6. PubMed PMID: 1667341.
3: Domingo MT, Piro F, Broquet C, Auclair E, Chabrier PE, Braquet P. Reversible or irreversible modification of [3H]PAF binding on rabbit platelet membranes differentiates various PAF receptor antagonists. Lipids. 1992 Aug;27(8):582-6. PubMed PMID: 1328798.