Metrifudil
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    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H341051

CAS#: 23707-33-7

Description: Metrifudil is an adenosine receptor agonist which displays some selectivity for the A2 receptor type.

Chemical Structure

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Metrifudil
CAS# 23707-33-7
Instruction

Theoretical Analysis

Hodoodo Cat#: H341051
Name: Metrifudil
CAS#: 23707-33-7
Chemical Formula: C18H21N5O4
Exact Mass: 371.16
Molecular Weight: 371.397
Elemental Analysis: C, 58.21; H, 5.70; N, 18.86; O, 17.23

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Metrifudil; Y-341; Y341; Y 341.

IUPAC/Chemical Name: 6-(o-Methylbenzylamino)-9-beta-D-ribofuranosyl-9H-purine

InChi Key: OOEMZCZWZXHBKW-SCFUHWHPSA-N

InChi Code: InChI=1S/C18H21N5O4/c1-10-4-2-3-5-11(10)6-19-16-13-17(21-8-20-16)23(9-22-13)18-15(26)14(25)12(7-24)27-18/h2-5,8-9,12,14-15,18,24-26H,6-7H2,1H3,(H,19,20,21)/t12-,14-,15-,18-/m1/s1

SMILES Code: Cc1ccccc1CNc2c3c(ncn2)n(cn3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 371.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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7: Reeves JJ, Coates J, Jarvis JE, Sheehan MJ, Strong P. Characterization of the adenosine receptor mediating contraction in rat colonic muscularis mucosae. Br J Pharmacol. 1993 Nov;110(3):1255-9. PubMed PMID: 8298815; PubMed Central PMCID: PMC2175831.

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10: Wilbrandt R, Frotscher U, Freyland M, Messerschmidt W, Richter R, Schulte-Lippern M, Zschaege B. [Treatment of glomerulonephritis with metrifudil. Preliminary report]. Med Klin. 1972 Sep 8;67(36):1138-40. German. PubMed PMID: 5073418.