WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H562559
CAS#: 1648707-58-7 (free base)
Description: UNC2170 Maleate is a ligand for the methyl-lysine binding protein, 53BP1.
Hodoodo Cat#: H562559
Name: UNC2170 Maleate
CAS#: 1648707-58-7 (free base)
Chemical Formula: C18H25BrN2O5
Exact Mass: 0.00
Molecular Weight: 429.310
Elemental Analysis: C, 50.36; H, 5.87; Br, 18.61; N, 6.53; O, 18.63
Synonym: UNC2170 Maleate; UNC-2170 Maleate; UNC 2170 Maleate;
IUPAC/Chemical Name: 3-Bromo-N-(3-tert-butylamino-propyl)-benzamide maleate salt
InChi Key: WCAATDGMINWXPJ-BTJKTKAUSA-N
InChi Code: InChI=1S/C14H21BrN2O.C4H4O4/c1-14(2,3)17-9-5-8-16-13(18)11-6-4-7-12(15)10-11;5-3(6)1-2-4(7)8/h4,6-7,10,17H,5,8-9H2,1-3H3,(H,16,18);1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES Code: O=C(NCCCNC(C)(C)C)C1=CC=CC(Br)=C1.O=C(O)/C=C\C(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 429.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Perfetti MT, Baughman BM, Dickson BM, Mu Y, Cui G, Mader P, Dong A, Norris JL,
Rothbart SB, Strahl BD, Brown PJ, Janzen WP, Arrowsmith CH, Mer G, McBride KM,
James LI, Frye SV. Identification of a fragment-like small molecule ligand for
the methyl-lysine binding protein, 53BP1. ACS Chem Biol. 2015 Apr
17;10(4):1072-81. doi: 10.1021/cb500956g. Epub 2015 Jan 28. PubMed PMID:
25590533; PubMed Central PMCID: PMC4402254.
