WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H341477
CAS#: 25332-05-2
Description: Jingsongling is a biochemical.
Hodoodo Cat#: H341477
Name: Jingsongling
CAS#: 25332-05-2
Chemical Formula: C11H14N2S
Exact Mass: 206.09
Molecular Weight: 206.307
Elemental Analysis: C, 64.04; H, 6.84; N, 13.58; S, 15.54
This product is not in stock, which may be available by custom synthesis.
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Synonym: Jingsongling; Xylazoline.
IUPAC/Chemical Name: 2-Thiazolamine, N-(2,6-dimethylphenyl)-4,5-dihydro- (9CI)
InChi Key: VLUXBNSRYHXDBV-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H14N2S/c1-8-4-3-5-9(2)10(8)13-11-12-6-7-14-11/h3-5H,6-7H2,1-2H3,(H,12,13)
SMILES Code: CC1=C(NC2=NCCS2)C(C)=CC=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 206.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Changmin H, Jianguo C, Dongming L, Guohong L, Mingxing D. Effects of xylazole alone and in combination with ketamine on the metabolic and neurohumoral responses in healthy dogs. Vet Anaesth Analg. 2010 Jul;37(4):322-8. doi: 10.1111/j.1467-2995.2010.00538.x. PubMed PMID: 20487431.
2: Tao R, Hjorth S. Alpha 2-adrenoceptor modulation of rat ventral hippocampal 5-hydroxytryptamine release in vivo. Naunyn Schmiedebergs Arch Pharmacol. 1992 Feb;345(2):137-43. PubMed PMID: 1349158.
3: Guo LQ, Huang RH. [Studies on biotransformation of jing song ling, a new anesthetic]. Yao Xue Xue Bao. 1990;25(2):95-100. Chinese. PubMed PMID: 2239329.
4: Hsu WH, Rong YF, Hembrough FB. The effects of jingsongling, a xylazine analog, on mean arterial blood pressure and heart rate in dogs--influences of yohimbine, tolazoline, prazosin, and atropine. J Vet Pharmacol Ther. 1989 Sep;12(3):283-8. PubMed PMID: 2810477.