Xyloidone

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H341491

CAS#: 15297-92-4

Description: Xyloidone is a biochemical.


Chemical Structure

img
Xyloidone
CAS# 15297-92-4

Theoretical Analysis

Hodoodo Cat#: H341491
Name: Xyloidone
CAS#: 15297-92-4
Chemical Formula: C15H12O3
Exact Mass: 240.08
Molecular Weight: 240.258
Elemental Analysis: C, 74.99; H, 5.03; O, 19.98

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Xyloidone; NSC 106453; NSC-106453; NSC106453; NSC 629748.

IUPAC/Chemical Name: 2H-Naphtho(2,3-b)pyran-5,10-dione, 2,2-dimethyl- (8CI)(9CI)

InChi Key: OWFHAMHRUCUSRM-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H12O3/c1-15(2)8-7-11-12(16)9-5-3-4-6-10(9)13(17)14(11)18-15/h3-8H,1-2H3

SMILES Code: O=C(C1=C2OC(C)(C)C=C1)C3=C(C2=O)C=CC=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 240.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Moraes DC, Curvelo JAR, Anjos CA, Moura KCG, Pinto MCFR, Portela MB, Soares RMA. β-lapachone and α-nor-lapachone modulate Candida albicans viability and virulence factors. J Mycol Med. 2018 Mar 26. pii: S1156-5233(17)30379-7. doi: 10.1016/j.mycmed.2018.03.004. [Epub ahead of print] PubMed PMID: 29598974.

2: Oliveira Silva E, Cruz de Carvalho T, Parshikov IA, Alves dos Santos R, Silva Emery F, Jacometti Cardoso Furtado NA. Cytotoxicity of lapachol metabolites produced by probiotics. Lett Appl Microbiol. 2014 Jul;59(1):108-14. doi: 10.1111/lam.12251. Epub 2014 Apr 9. PubMed PMID: 24635204.

3: Garkavtsev I, Chauhan VP, Wong HK, Mukhopadhyay A, Glicksman MA, Peterson RT, Jain RK. Dehydro-alpha-lapachone, a plant product with antivascular activity. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11596-601. doi: 10.1073/pnas.1104225108. Epub 2011 Jun 27. PubMed PMID: 21709229; PubMed Central PMCID: PMC3136298.

4: Nasiri HR, Bolte M, Schwalbe H. Electrochemical and crystal structural analysis of alpha- and dehydro-alpha-lapachones. Nat Prod Res. 2008;22(14):1225-1230. doi: 10.1080/14786410701654925. PubMed PMID: 18932085.

5: Cho JY, Kim HY, Choi GJ, Jang KS, Lim HK, Lim CH, Cho KY, Kim JC. Dehydro-alpha-lapachone isolated from Catalpa ovata stems: activity against plant pathogenic fungi. Pest Manag Sci. 2006 May;62(5):414-8. PubMed PMID: 16550502.

6: Müller K, Sellmer A, Wiegrebe W. Potential antipsoriatic agents: lapacho compounds as potent inhibitors of HaCaT cell growth. J Nat Prod. 1999 Aug;62(8):1134-6. PubMed PMID: 10479319.

7: Pinto AV, Ferreira VF, Coutada LC. [Synthesis of xyloidone and lapachone analogs]. An Acad Bras Cienc. 1980 Sep;52(3):477-9. Portuguese. PubMed PMID: 7011134.