WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H341591
CAS#: 49561-54-8
Description: Wd 67-2 is a biochemical.
Hodoodo Cat#: H341591
Name: Wd 67-2
CAS#: 49561-54-8
Chemical Formula: C19H24ClN3O
Exact Mass: 345.16
Molecular Weight: 345.871
Elemental Analysis: C, 65.98; H, 6.99; Cl, 10.25; N, 12.15; O, 4.63
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Synonym: Wd 67-2; Wd-67-2; Wd67-2
IUPAC/Chemical Name: 1,2,4-Oxadiazole, 4-(2-(alpha-methylphenethylamino)ethyl)-3-phenyl-, monohydrochloride
InChi Key: VEIOSCDVDPNHPJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H23N3O.ClH/c1-16(14-17-8-4-2-5-9-17)20-12-13-22-15-23-21-19(22)18-10-6-3-7-11-18;/h2-11,16,20H,12-15H2,1H3;1H
SMILES Code: CC(NCCN1C(C2=CC=CC=C2)=NOC1)CC3=CC=CC=C3.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 345.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Lamarca A, Nonaka D, Breitwieser W, Ashton G, Barriuso J, McNamara MG, Moghadam S, Rogan J, Mansoor W, Hubner RA, Clark C, Chakrabarty B, Valle JW. PD-L1 expression and presence of TILs in small intestinal neuroendocrine tumours. Oncotarget. 2018 Feb 12;9(19):14922-14938. doi: 10.18632/oncotarget.24464. eCollection 2018 Mar 13. PubMed PMID: 29599916; PubMed Central PMCID: PMC5871087.
2: Dalla Vedova R, D'Alò G. [Study of Wd 67-2, a new synthetic anorectic agent]. Boll Chim Farm. 1973 Apr;112(4):273-82. Italian. PubMed PMID: 4721650.