WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H584433
CAS#: 621-79-4
Description: Cinnamamide is an amide of trans-cinnamic acid and a metabolite of Streptomyces that reduced tumor weight in a mouse model of C26 murine colon carcinoma, in vivo.
Hodoodo Cat#: H584433
Name: Cinnamamide
CAS#: 621-79-4
Chemical Formula: C9H9NO
Exact Mass: 147.07
Molecular Weight: 147.177
Elemental Analysis: C, 73.45; H, 6.16; N, 9.52; O, 10.87
Synonym: Cinnamamide, NSC 32953
IUPAC/Chemical Name: 3-phenyl-2-propenamide
InChi Key: APEJMQOBVMLION-VOTSOKGWSA-N
InChi Code: InChI=1S/C9H9NO/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H2,10,11)/b7-6+
SMILES Code: O=C(N)/C=C/C1=CC=CC=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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| In vitro activity: | |
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The following data is based on the product molecular weight 147.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1. Sekizawa, Y. Trans-cinnamic acide amide as a metabolic product of Streptomyces. J. Biochem. 45(1), 9-11 (1958).
2. Jiang, X.-f., and Zhen, Y.-s. Cinnamamide, an antitumor agent with low cytotoxicity acting on matrix metalloproteinase. Anticancer Drugs 11(1), 49-54 (2000).
3. Gurney, J.E., Watkins, R.W., Gill, E.L., et al. Non-lethal mouse repellents: evaluation of cinnamamide as a repellent against commensal and field rodents. Appl. Annimal Behav. Sci. 49(4), 353-363 (1996).
