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Trifluralin
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WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H596526

CAS#: 1582-09-8

Description: Trifluralin is a microtubule-disrupting pre-emergence herbicide.

Chemical Structure

Trifluralin

CAS# 1582-09-8

Instruction

Theoretical Analysis

Hodoodo Cat#: H596526
Name: Trifluralin
CAS#: 1582-09-8
Chemical Formula: C13H16F3N3O4
Exact Mass: 335.11
Molecular Weight: 335.280
Elemental Analysis: C, 46.57; H, 4.81; F, 17.00; N, 12.53; O, 19.09

Price and Availability

Size	Price	Availability	Quantity
250mg	USD 220
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. Hodoodo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Trifluralin; Elancolan; Nitran; Treficon; TRI-4; L-36352; L 36352; 36352;

IUPAC/Chemical Name: 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline

InChi Key: ZSDSQXJSNMTJDA-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3

SMILES Code: FC(C1=CC([N+]([O-])=O)=C(N(CCC)CCC)C([N+]([O-])=O)=C1)(F)F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 335.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Chu B, Eivazi F. Enhanced Dissipation of Selected Herbicides in a Simulated Organic Matrix Biobed: A System to Control On-Farm Point-Source Pollution. J Environ Qual. 2018 Mar;47(2):221-227. doi: 10.2134/jeq2016.04.0124. PubMed PMID: 29634810.

2: Denaeghel HER, Van Laere K, Leus L, Lootens P, Van Huylenbroeck J, Van Labeke MC. The Variable Effect of Polyploidization on the Phenotype in Escallonia. Front Plant Sci. 2018 Mar 20;9:354. doi: 10.3389/fpls.2018.00354. eCollection 2018. PubMed PMID: 29616065; PubMed Central PMCID: PMC5869194.

3: Chu Z, Chen J, Nyporko A, Han H, Yu Q, Powles S. Novel α-Tubulin Mutations Conferring Resistance to Dinitroaniline Herbicides in Lolium rigidum. Front Plant Sci. 2018 Feb 6;9:97. doi: 10.3389/fpls.2018.00097. eCollection 2018. PubMed PMID: 29472938; PubMed Central PMCID: PMC5810296.

4: Goto Y, Sudo M. Uptake and elimination kinetics of trifluralin and pendimethalin in Pheretima spp. and Eisenia spp. Environ Sci Pollut Res Int. 2018 May;25(13):12352-12360. doi: 10.1007/s11356-018-1483-7. Epub 2018 Feb 18. PubMed PMID: 29455354.

5: Hasanzadeh A, Khataee A, Zarei M, Joo SW. Photo-assisted electrochemical abatement of trifluralin using a cathode containing a C(60)-carbon nanotubes composite. Chemosphere. 2018 May;199:510-523. doi: 10.1016/j.chemosphere.2018.02.061. Epub 2018 Feb 9. PubMed PMID: 29454173.

6: Sarıgöl Kılıç Z, Aydın S, Ündeğer Bucurgat Ü, Başaran N. In vitro genotoxicity assessment of dinitroaniline herbicides pendimethalin and trifluralin. Food Chem Toxicol. 2018 Mar;113:90-98. doi: 10.1016/j.fct.2018.01.034. Epub 2018 Jan 31. PubMed PMID: 29374591.

7: Berton A, Brugnera MF, Dores EFGC. Grab and passive sampling applied to pesticide analysis in the São Lourenço river headwater in Campo Verde - MT, Brazil. J Environ Sci Health B. 2018 Apr 3;53(4):237-245. doi: 10.1080/03601234.2017.1410412. Epub 2018 Jan 16. PubMed PMID: 29336664.

8: Liu L, Tang J, Zhong G, Zhen X, Pan X, Tian C. Spatial distribution and seasonal variation of four current-use pesticides (CUPs) in air and surface water of the Bohai Sea, China. Sci Total Environ. 2018 Apr 15;621:516-523. doi: 10.1016/j.scitotenv.2017.11.282. Epub 2017 Nov 28. PubMed PMID: 29195200.

9: Chen J, Yu Q, Owen M, Han H, Powles S. Dinitroaniline herbicide resistance in a multiple-resistant Lolium rigidum population. Pest Manag Sci. 2018 Apr;74(4):925-932. doi: 10.1002/ps.4790. Epub 2018 Feb 1. PubMed PMID: 29148165.

10: Bisceglia KJ, Dharia M, Kaur M, Pavlovici FA. Leachability and potential ecotoxic impact of trifluralin-impregnated mulch. Environ Sci Pollut Res Int. 2018 Jan;25(3):2972-2980. doi: 10.1007/s11356-017-0575-0. Epub 2017 Nov 16. PubMed PMID: 29147986.

11: Bengtson Nash SM, Wild SJ, Hawker DW, Cropp RA, Hung H, Wania F, Xiao H, Bohlin-Nizzetto P, Bignert A, Broomhall S. Persistent Organic Pollutants in the East Antarctic Atmosphere: Inter-Annual Observations from 2010 to 2015 Using High-Flow-Through Passive Sampling. Environ Sci Technol. 2017 Dec 5;51(23):13929-13937. doi: 10.1021/acs.est.7b04224. Epub 2017 Nov 21. PubMed PMID: 29120176.

12: Sousa JCG, Ribeiro AR, Barbosa MO, Pereira MFR, Silva AMT. A review on environmental monitoring of water organic pollutants identified by EU guidelines. J Hazard Mater. 2018 Feb 15;344:146-162. doi: 10.1016/j.jhazmat.2017.09.058. Epub 2017 Oct 3. Review. PubMed PMID: 29032095.

13: Ferro ÉC, Cardoso CAL, Arruda GJ. Voltammetric detection of trifluralin in tap water, fruit juice, and vegetable extracts in the presence of surfactants. J Environ Sci Health B. 2017 Oct 3;52(10):762-769. doi: 10.1080/03601234.2017.1356679. PubMed PMID: 29022832.

14: Karasali H, Pavlidis G, Marousopoulou A, Ambrus A. Occurrence and distribution of trifluralin, ethalfluralin, and pendimethalin in soils used for long-term intensive cotton cultivation in central Greece. J Environ Sci Health B. 2017 Oct 3;52(10):719-728. doi: 10.1080/03601234.2017.1356678. Epub 2017 Sep 22. PubMed PMID: 28937929.

15: Franco-Bernardes MF, Rocha OP, Pereira LC, Tasso MJ, Meireles G, de Oliveira DP, Dorta DJ. The herbicides trifluralin and tebuthiuron have no genotoxic or mutagenic potential as evidenced by genetic tests. Environ Sci Pollut Res Int. 2017 Oct;24(30):24029-24037. doi: 10.1007/s11356-017-9966-5. Epub 2017 Sep 6. PubMed PMID: 28879624.

16: Faulkner C, Zhou J, Evrard A, Bourdais G, MacLean D, Häweker H, Eckes P, Robatzek S. An automated quantitative image analysis tool for the identification of microtubule patterns in plants. Traffic. 2017 Oct;18(10):683-693. doi: 10.1111/tra.12505. Epub 2017 Aug 16. PubMed PMID: 28746801.

17: Epp JB, Schmitzer PR, Crouse GD. Fifty years of herbicide research: comparing the discovery of trifluralin and halauxifen-methyl. Pest Manag Sci. 2018 Jan;74(1):9-16. doi: 10.1002/ps.4657. Epub 2017 Aug 24. PubMed PMID: 28675627.

18: Gorito AM, Ribeiro AR, Almeida CMR, Silva AMT. A review on the application of constructed wetlands for the removal of priority substances and contaminants of emerging concern listed in recently launched EU legislation. Environ Pollut. 2017 Aug;227:428-443. doi: 10.1016/j.envpol.2017.04.060. Epub 2017 May 6. Review. PubMed PMID: 28486186.

19: G Silva M, Knowles DP, Antunes S, Domingos A, Esteves MA, Suarez CE. Inhibition of the in vitro growth of Babesia bigemina, Babesia caballi and Theileria equi parasites by trifluralin analogues. Ticks Tick Borne Dis. 2017 Jun;8(4):593-597. doi: 10.1016/j.ttbdis.2017.04.002. Epub 2017 Apr 10. PubMed PMID: 28416183.

20: Heidar H, Seyed Taghi Omid N, Abbasali Z. Monitoring Organophosphorous Pesticides Residues in the Shahid Rajaei Dam Reservoir, Sari, Iran. Bull Environ Contam Toxicol. 2017 Jun;98(6):791-797. doi: 10.1007/s00128-017-2080-z. Epub 2017 Apr 12. PubMed PMID: 28405693.

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Trifluralin featured