WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H596568
CAS#: 70483-69-1
Description: L 634549 is a bioactive chemical.
Hodoodo Cat#: H596568
Name: L 634549
CAS#: 70483-69-1
Chemical Formula: C11H14N4O5
Exact Mass: 282.10
Molecular Weight: 282.250
Elemental Analysis: C, 46.81; H, 5.00; N, 19.85; O, 28.34
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: L 634549; L-634549; L634549; L634,549; L 634,549; L-634,549;
IUPAC/Chemical Name: 3-(1-methyl-5-nitro-1H-imidazol-2-yl)-3a,4,5,6,7,7a-hexahydrobenzo[d]isoxazole-6,7-diol
InChi Key: ZAYDDXBAZPKGDR-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H14N4O5/c1-14-7(15(18)19)4-12-11(14)8-5-2-3-6(16)9(17)10(5)20-13-8/h4-6,9-10,16-17H,2-3H2,1H3
SMILES Code: OC1CCC2C(C3=NC=C([N+]([O-])=O)N3C)=NOC2C1O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 282.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Jennings FW. Chemotherapy of CNS-trypanosomiasis: the combined use of the arsenicals and nitro-compounds. Trop Med Parasitol. 1991 Jun;42(2):139-42. PubMed PMID: 1896771.
2: Jennings FW, Urquhart GM, Murray PK, Miller BM. The use of 2-substituted 5-nitroimidazoles in the treatment of chronic murine Trypanosoma brucei infections with central nervous system involvement. Z Parasitenkd. 1984;70(6):691-7. PubMed PMID: 6524019.
3: Jennings FW, Urquhart GM, Murray PK, Miller BM. Treatment with suramin and 2-substituted 5-nitroimidazoles of chronic murine Trypanosoma brucei infections with central nervous system involvement. Trans R Soc Trop Med Hyg. 1983;77(5):693-8. PubMed PMID: 6659049.