WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H559177
CAS#: 74313-95-4
Description: L-DPPG is a bioacive chemical.
Hodoodo Cat#: H559177
Name: L-DPPG
CAS#: 74313-95-4
Chemical Formula: C38H76O11P
Exact Mass: 739.51
Molecular Weight: 739.980
Elemental Analysis: C, 61.68; H, 10.35; O, 23.78; P, 4.19
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: L-DPPG; L DPPG; LDPPG; L-Dipalmitoylphosphatidylglycerol;
IUPAC/Chemical Name: rac-(2,3-dihydroxy-1-((((R)-3-hydroxy-2-(palmitoyloxy)propyl)(palmitoyl)-l3-oxidanyl)oxy)propyl)phosphonic acid
InChi Key: DGOAUGUBHWEONY-KSYHHVMSSA-N
InChi Code: InChI=1S/C38H76O11P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(42)47-34(31-39)33-49(48-38(35(41)32-40)50(44,45)46)37(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h34-35,38-41H,3-33H2,1-2H3,(H2,44,45,46)/t34-,35?,38?/m0/s1
SMILES Code: OC[C@H](OC(CCCCCCCCCCCCCCC)=O)CO(OC(P(O)(O)=O)C(CO)O)C(CCCCCCCCCCCCCCC)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 739.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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6: Kafle A, Misono T, Bhadani A, Akamatsu M, Sakai K, Kaise C, Kaneko T, Sakai H. Effects of β-Sitosteryl Sulfate on the Phase Behavior and Hydration Properties of Distearoylphosphatidylcholine: a Comparison with Dipalmitoylphosphatidylcholine. J Oleo Sci. 2018 Apr 1;67(4):433-443. doi: 10.5650/jos.ess17182. Epub 2018 Mar 9. PubMed PMID: 29526873.
7: Eedara BB, Rangnekar B, Doyle C, Cavallaro A, Das SC. The influence of surface active l-leucine and 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) in the improvement of aerosolization of pyrazinamide and moxifloxacin co-spray dried powders. Int J Pharm. 2018 May 5;542(1-2):72-81. doi: 10.1016/j.ijpharm.2018.03.005. Epub 2018 Mar 7. PubMed PMID: 29524618.
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12: Kafle A, Misono T, Bhadani A, Sakai K, Kaise C, Kaneko T, Sakai H. Effects of sodium β-sitosteryl sulfate on the phase behavior of dipalmitoylphosphatidylcholine. Colloids Surf B Biointerfaces. 2018 Jan 1;161:59-66. doi: 10.1016/j.colsurfb.2017.10.014. Epub 2017 Oct 6. PubMed PMID: 29040835.
13: Zhang H, Dudley EG, Harte F. Critical Synergistic Concentration of Lecithin Phospholipids Improves the Antimicrobial Activity of Eugenol against Escherichia coli. Appl Environ Microbiol. 2017 Oct 17;83(21). pii: e01583-17. doi: 10.1128/AEM.01583-17. Print 2017 Nov 1. PubMed PMID: 28842540; PubMed Central PMCID: PMC5648912.
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20: Palominos MA, Vilches D, Bossel E, Soto-Arriaza MA. Interaction between amphipathic triblock copolymers and L-α-dipalmitoyl phosphatidylcholine large unilamellar vesicles. Colloids Surf B Biointerfaces. 2016 Dec 1;148:30-40. doi: 10.1016/j.colsurfb.2016.08.038. Epub 2016 Aug 27. PubMed PMID: 27591568.
