WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H597111
CAS#: 5996-22-5
Description: Calcium diglutamate, sometimes abbreviated CDG is a calcium acid salt of glutamic acid. CDG is a flavor enhancer (E number E623) — it is the calcium analog of monosodium glutamate (MSG). Because the glutamate is the actual flavor-enahancer, CDG has the same flavor-enhancing properties as MSG, but without the increased sodium content. As a soluble source of calcium ions, this chemical is also used as a first-aid treatment for exposure to hydrofluoric acid.
Hodoodo Cat#: H597111
Name: Calcium diglutamate
CAS#: 5996-22-5
Chemical Formula: C10H16CaN2O8
Exact Mass: 0.00
Molecular Weight: 332.320
Elemental Analysis: C, 36.14; H, 4.85; Ca, 12.06; N, 8.43; O, 38.51
This product is not in stock, which may be available by custom synthesis.
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Synonym: Calcium diglutamate; Calcium di-L-glutamate; Glutamic acid, calcium salt (2:1), L-;
IUPAC/Chemical Name: calcium (S)-2-amino-4-carboxybutanoate
InChi Key: UMVAYAXXQSFULN-QHTZZOMLSA-L
InChi Code: InChI=1S/2C5H9NO4.Ca/c2*6-3(5(9)10)1-2-4(7)8;/h2*3H,1-2,6H2,(H,7,8)(H,9,10);/q;;+2/p-2/t2*3-;/m00./s1
SMILES Code: N[C@@H](CCC(O)=O)C([O-])=O.N[C@@H](CCC(O)=O)C([O-])=O.[Ca+2]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 332.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Bain JL, Culpepper BK, Reddy MS, Bellis SL. Comparing variable-length polyglutamate domains to anchor an osteoinductive collagen-mimetic peptide to diverse bone grafting materials. Int J Oral Maxillofac Implants. 2014 Nov-Dec;29(6):1437-45. doi: 10.11607/jomi.3759. PubMed PMID: 25397807; PubMed Central PMCID: PMC4504020.
2: Türkoğlu Ş. Evaluation of genotoxic effects of five flavour enhancers (glutamates) on the root meristem cells of Allium cepa. Toxicol Ind Health. 2015 Sep;31(9):792-801. doi: 10.1177/0748233713475509. Epub 2013 Feb 1. PubMed PMID: 23377115.
3: Ball P, Woodward D, Beard T, Shoobridge A, Ferrier M. Calcium diglutamate improves taste characteristics of lower-salt soup. Eur J Clin Nutr. 2002 Jun;56(6):519-23. PubMed PMID: 12032651.
4: Schiffman SS, Frey AE, Luboski JA, Foster MA, Erickson RP. Taste of glutamate salts in young and elderly subjects: role of inosine 5'-monophosphate and ions. Physiol Behav. 1991 May;49(5):843-54. PubMed PMID: 1715997.