WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H591813
CAS#: 621-87-4
Description: Phenoxyacetone causes Acetylcholinesterase inhibition.
Hodoodo Cat#: H591813
Name: Phenoxyacetone
CAS#: 621-87-4
Chemical Formula: C9H10O2
Exact Mass: 150.07
Molecular Weight: 150.177
Elemental Analysis: C, 71.98; H, 6.71; O, 21.31
Synonym: Phenoxyacetone; NSC 1876; NSC-1876; NSC1876
IUPAC/Chemical Name: 2-Propanone, 1-phenoxy-
InChi Key: QWAVNXZAQASOML-UHFFFAOYSA-N
InChi Code: InChI=1S/C9H10O2/c1-8(10)7-11-9-5-3-2-4-6-9/h2-6H,7H2,1H3
SMILES Code: CC(COC1=CC=CC=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 150.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Dafforn A, Neenan JP, Ash CE, Betts L, Finke JM, Garman JA, Rao M, Walsh K, Williams RR. Acetylcholinesterase inhibition by the ketone transition state analog phenoxyacetone and 1-halo-3-phenoxy-2-propanones. Biochem Biophys Res Commun. 1982 Jan 29;104(2):597-602. PubMed PMID: 7073703.
2: Landquist JK. Oxidative cyclisation of ketone thiosemicarbazones. II. Derivatives of phenoxyacetone. J Chem Soc Perkin 1. 1970;2:323-4. PubMed PMID: 5460862.