WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H597313
CAS#: 110326-15-3
Description: 1'-Ethylascorbigen releases ascorbic acid in acidic solution; leads to increase of the cells' ability to produce PGE2 & LTB4. It has been shown to inhibit growth of experimental murine tumors.
Hodoodo Cat#: H597313
Name: 1'-Ethylascorbigen
CAS#: 110326-15-3
Chemical Formula: C17H19NO6
Exact Mass: 333.12
Molecular Weight: 333.340
Elemental Analysis: C, 61.25; H, 5.75; N, 4.20; O, 28.80
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Synonym: 1'-Ethylascorbigen;
IUPAC/Chemical Name: (S)-2-((2S,4R)-2,4-dihydroxytetrahydrofuran-2-yl)-2-hydroxy-3-(1-vinyl-1H-indol-3-yl)propanoic acid
InChi Key: UXUSIDWAMDGXAF-JLZZUVOBSA-N
InChi Code: InChI=1S/C17H19NO6/c1-2-18-9-11(13-5-3-4-6-14(13)18)7-16(22,15(20)21)17(23)8-12(19)10-24-17/h2-6,9,12,19,22-23H,1,7-8,10H2,(H,20,21)/t12-,16-,17+/m1/s1
SMILES Code: C=Cn1c2ccccc2c(C[C@@]([C@]3(O)C[C@@H](O)CO3)(O)C(O)=O)c1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 333.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Efimov S, Shevchenko V, Shchukin I, Preobrazhenskaya M. The influence of 1'-methyl- and 1'-ethylascorbigen on metabolism of arachidonic acid in murine spleen cells. Biochem Biophys Res Commun. 1993 Feb 15;190(3):895-900. PubMed PMID: 8382491.
2: Bukin IuV, Plikhtiak IL, Draudin-Krylenko VA, Iartseva IV, Orlova LM. [Ascorbigen and its derivatives--depot preparations of ascorbic acid]. Bioorg Khim. 1987 Apr;13(4):539-45. Russian. PubMed PMID: 3606674.