17-Oxosparteine

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H597700

CAS#: 489-72-5

Description: 17-Oxosparteine is a minor urinary metabolite of sparteine in man.

Chemical Structure

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17-Oxosparteine
CAS# 489-72-5
Instruction

Theoretical Analysis

Hodoodo Cat#: H597700
Name: 17-Oxosparteine
CAS#: 489-72-5
Chemical Formula: C15H24N2O
Exact Mass: 248.19
Molecular Weight: 248.370
Elemental Analysis: C, 72.54; H, 9.74; N, 11.28; O, 6.44

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: 17-Oxosparteine; NSC 127496; NSC-127496; NSC127496; Oxysparteine; Oxysparteine;

IUPAC/Chemical Name: (7R,7aR,14S,14aS)-dodecahydro-2H,6H-7,14-methanodipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one

InChi Key: YQMWQSMYVPLYDI-RFQIPJPRSA-N

InChi Code: InChI=1S/C15H24N2O/c18-15-12-9-11(13-5-2-4-8-17(13)15)10-16-7-3-1-6-14(12)16/h11-14H,1-10H2/t11-,12+,13-,14+/m0/s1

SMILES Code: O=C1[C@@](C2)([H])[C@](CCCC3)([H])N3C[C@@]2([H])[C@@]4([H])N1CCCC4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 248.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Ritchie JC, Mitchell SC, Smith RL, Zhang AQ. Use of site-specified tritium labelling to confirm the formation of 17-oxosparteine as a minor urinary metabolite of sparteine in man. Xenobiotica. 1996 Sep;26(9):977-82. PubMed PMID: 8893044.

2: Ebner T, Meese CO, Eichelbaum M. Mechanism of cytochrome P450 2D6-catalyzed sparteine metabolism in humans. Mol Pharmacol. 1995 Dec;48(6):1078-86. PubMed PMID: 8848008.

3: Kim IC, Balandrin MF, Kinghorn AD. Reinvestigation of the alkaloids of Lupinus sericeus Pursh. Identification of a new natural product, 10,17-dioxo-beta-isosparteine. J Agric Food Chem. 1982 Jul-Aug;30(4):796-8. PubMed PMID: 7119288.