Stearyl tyrosine

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H598069

CAS#: 73393-27-8

Description: Stearyl tyrosine is an immunoadjuvants, long-chain stearyl ester of amino acids and peptides.

Chemical Structure

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Stearyl tyrosine
CAS# 73393-27-8
Instruction

Theoretical Analysis

Hodoodo Cat#: H598069
Name: Stearyl tyrosine
CAS#: 73393-27-8
Chemical Formula: C27H47NO3
Exact Mass: 433.36
Molecular Weight: 433.670
Elemental Analysis: C, 74.78; H, 10.92; N, 3.23; O, 11.07

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Stearyl tyrosine; Stearyl-tyrosine; Stearyltyrosine;

IUPAC/Chemical Name: octadecyl L-tyrosinate

InChi Key: OZSVSBMHEZAZTL-SANMLTNESA-N

InChi Code: InChI=1S/C27H47NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22-31-27(30)26(28)23-24-18-20-25(29)21-19-24/h18-21,26,29H,2-17,22-23,28H2,1H3/t26-/m0/s1

SMILES Code: N[C@@H](CC1=CC=C(O)C=C1)C(OCCCCCCCCCCCCCCCCCC)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 433.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Penney CL, Ethier D, Dionne G, Nixon-George A, Zaghouani H, Michon F, Jennings H, Bona CA. Further studies on the adjuvanticity of stearyl tyrosine and ester analogues. Vaccine. 1993;11(11):1129-34. PubMed PMID: 8249432.

2: Gupta RK, Siber GR. Comparison of adjuvant activities of aluminium phosphate, calcium phosphate and stearyl tyrosine for tetanus toxoid. Biologicals. 1994 Mar;22(1):53-63. PubMed PMID: 8068314.

3: Penney CL, Dionne G, Nixon-George A, Bona CA. Further studies on the adjuvanticity of stearyl tyrosine and amide analogues. Vaccine. 1994 May;12(7):629-32. PubMed PMID: 8085381.

4: Landi S, Penney CL, Shah P, Hart F, Campbell JB, Cucakovich N. Adjuvanticity of stearyl tyrosine on inactivated poliovirus vaccine. Vaccine. 1986 Jun;4(2):99-104. PubMed PMID: 3014774.

5: Nixon-George A, Moran T, Dionne G, Penney CL, Lafleur D, Bona CA. The adjuvant effect of stearyl tyrosine on a recombinant subunit hepatitis B surface antigen. J Immunol. 1990 Jun 15;144(12):4798-802. PubMed PMID: 2351829.

6: Nixon A, Zaghouani H, Penney CL, Lacroix M, Dionne G, Anderson SA, Kennedy RC, Bona CA. Adjuvanticity of stearyl tyrosine on the antibody response to peptide 503-535 from HIV gp160. Viral Immunol. 1992 Summer;5(2):141-50. PubMed PMID: 1616585.

7: Penney C. Stearyl tyrosine. An organic equivalent of aluminum-based immunoadjuvants. Pharm Biotechnol. 1995;6:611-24. Review. PubMed PMID: 7551239.

8: Bona C, Nixon A, Kennedy R, Zaghouani H. Adjuvanticity of stearyl tyrosine on the antibody response to peptide 503-535 from HIV gp160. AIDS Res Hum Retroviruses. 1992 Aug;8(8):1377. PubMed PMID: 1466959.

9: Penney CL, Landi S, Shah P, Leung KH, Archer MC. Analysis of the immunoadjuvant octadecyl tyrosine hydrochloride. J Biol Stand. 1986 Oct;14(4):345-9. PubMed PMID: 3558418.

10: Arora DJ, Houde M. Modulation of murine macrophage responses stimulated with influenza glycoproteins. Can J Microbiol. 1992 Mar;38(3):188-92. PubMed PMID: 1393819.

11: Von Seefried A, Chun JH, Grant JA, Letvenuk L, Pearson EW. Inactivated poliovirus vaccine and test development at Connaught Laboratories Ltd. Rev Infect Dis. 1984 May-Jun;6 Suppl 2:S345-9. PubMed PMID: 6330837.

12: Penney C, Shah P, Landi S. The interaction of slow-release immunoadjuvants with selected antigens measured in vitro. J Biol Stand. 1985 Jan;13(1):43-52. PubMed PMID: 3988778.