Ganodermadiol

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H598358

CAS#: 104700-96-1

Description: Ganodermadiol is a lanostanoid isolated from Ganoderma lucidum.

Chemical Structure

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Ganodermadiol
CAS# 104700-96-1
Instruction

Theoretical Analysis

Hodoodo Cat#: H598358
Name: Ganodermadiol
CAS#: 104700-96-1
Chemical Formula: C30H48O2
Exact Mass: 440.37
Molecular Weight: 440.710
Elemental Analysis: C, 81.76; H, 10.98; O, 7.26

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Ganodermadiol; (+)-Ganoderol B; Ganoderol B;

IUPAC/Chemical Name: (3S,5R,10S,13R,14R,17R)-17-((R,E)-7-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethyl-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

InChi Key: AOXXVRDKZLRGTJ-AZIDVCJLSA-N

InChi Code: InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1

SMILES Code: CC1(C)[C@@H](O)CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C)CC/C=C(C)/CO)CC[C@](C)4C3=CC[C@@]12[H]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 440.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Arisawa M, Fujita A, Saga M, Fukumura H, Hayashi T, Shimizu M, Morita N. Three new lanostanoids from Ganoderma lucidum. J Nat Prod. 1986 Jul-Aug;49(4):621-5. PubMed PMID: 3783158.

2: Vazirian M, Faramarzi MA, Ebrahimi SE, Esfahani HR, Samadi N, Hosseini SA, Asghari A, Manayi A, Mousazadeh A, Asef MR, Habibi E, Amanzadeh Y. Antimicrobial effect of the Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (higher Basidiomycetes) and its main compounds. Int J Med Mushrooms. 2014;16(1):77-84. PubMed PMID: 24940906.

3: Mothana RA, Awadh Ali NA, Jansen R, Wegner U, Mentel R, Lindequist U. Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferi. Fitoterapia. 2003 Feb;74(1-2):177-80. PubMed PMID: 12628419.

4: Li B, Lee DS, Kang Y, Yao NQ, An RB, Kim YC. Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes. Food Chem Toxicol. 2013 Mar;53:317-24. doi: 10.1016/j.fct.2012.12.016. Epub 2012 Dec 21. PubMed PMID: 23266269.

5: Gao JJ, Min BS, Ahn EM, Nakamura N, Lee HK, Hattori M. New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells. Chem Pharm Bull (Tokyo). 2002 Jun;50(6):837-40. PubMed PMID: 12045343.

6: Dai J, Miller MA, Everetts NJ, Wang X, Li P, Li Y, Xu JH, Yao G. Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum. Oncotarget. 2017 Feb 21;8(8):13770-13781. doi: 10.18632/oncotarget.14634. PubMed PMID: 28099150; PubMed Central PMCID: PMC5355137.