WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H461265
CAS#: 101820-46-6
Description: Rev 5975 is a non-sulfhydryl containing ACE-inhibitor.
Hodoodo Cat#: H461265
Name: Rev 5975
CAS#: 101820-46-6
Chemical Formula: C24H30N2O5
Exact Mass: 426.22
Molecular Weight: 426.510
Elemental Analysis: C, 67.59; H, 7.09; N, 6.57; O, 18.76
This product is not in stock, which may be available by custom synthesis.
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Synonym: Rev 5975; Rev 5975; Rev 5975;
IUPAC/Chemical Name: N-benzyl-N-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)glycine
InChi Key: IKWSMOBSRGJBSI-RXVVDRJESA-N
InChi Code: InChI=1S/C24H30N2O5/c1-3-31-24(30)21(15-14-19-10-6-4-7-11-19)25-18(2)23(29)26(17-22(27)28)16-20-12-8-5-9-13-20/h4-13,18,21,25H,3,14-17H2,1-2H3,(H,27,28)/t18-,21-/m0/s1
SMILES Code: O=C(O)CN(C([C@H](C)N[C@H](C(OCC)=O)CCC1=CC=CC=C1)=O)CC2=CC=CC=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 426.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Hütter JF, Dehn A, Schmidt W. Hemodynamic effects of new angiotensin
converting enzyme inhibitors during continuous angiotensin I infusion on
conscious dogs. Arzneimittelforschung. 1988 Jul;38(7):896-901. PubMed PMID:
2849951.