WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H598743
CAS#: 77215-53-3
Description: Levorin A0 is a Levorin component.
Hodoodo Cat#: H598743
Name: Levorin A0
CAS#: 77215-53-3
Chemical Formula: C59H84N2O17
Exact Mass: 1,092.58
Molecular Weight: 1,093.318
Elemental Analysis: C, 64.82; H, 7.74; N, 2.56; O, 24.88
This product is not in stock, which may be available by custom synthesis.
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Synonym: Levorin A0; Levorin-A0; LevorinA0;
IUPAC/Chemical Name: (23E,25E,27E,29E,31E,33E,35E)-22-((4-amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-38-(7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl)-10,14,18,20-tetrahydroxy-37-methyl-2,4,8,16-tetraoxooxacyclooctatriaconta-23,25,27,29,31,33,35-heptaene-19-carboxylic acid
InChi Key: WGGISROKTUVKFG-AJJHKJIKSA-N
InChi Code: InChI=1S/C59H84N2O17/c1-36-19-15-13-11-9-7-5-6-8-10-12-14-16-24-47(77-59-56(73)54(61)55(72)39(4)76-59)34-51(70)53(58(74)75)50(69)32-46(66)31-44(64)22-17-20-42(62)30-43(63)21-18-23-45(65)33-52(71)78-57(36)38(3)29-37(2)48(67)35-49(68)40-25-27-41(60)28-26-40/h5-16,19,24-28,36-39,42,44,47-48,50-51,53-57,59,62,64,67,69-70,72-73H,17-18,20-23,29-35,60-61H2,1-4H3,(H,74,75)/b6-5+,9-7+,10-8+,13-11+,14-12+,19-15+,24-16+
SMILES Code: CC1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/C(OC2C(O)C(N)C(O)C(C)O2)CC(O)C(C(O)=O)C(O)CC(CC(O)CCCC(O)CC(CCCC(CC(OC1C(CC(C(O)CC(c3ccc(N)cc3)=O)C)C)=O)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 1,093.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Malkov MA, Golubeva LA, L'vova LE. [Biosynthesis of the components of levorin and fatty acids in the process of Str. levoris cultivation]. Antibiotiki. 1980 Dec;25(12):895-8. Russian. PubMed PMID: 7469393.
2: Kasumov KhM, Samedova AA, Shenin IuD. [Mechanism of the interaction of the individual components of levorin and nystatin preparations with lipid membranes]. Antibiot Med Biotekhnol. 1987 Nov;32(11):824-8. Russian. PubMed PMID: 2449860.
