WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H555303
CAS#: Unknown
Description: NOSO-95179 is an antibacterial compound that bind to the bacterial ribosome and kill bacteria through inhibition of the translation. NOSO-95C showed promising in vitro and in vivo efficacy against Enterobacteriaceae.
Hodoodo Cat#: H555303
Name: NOSO-95179
CAS#: Unknown
Chemical Formula: C44H77N17O11
Exact Mass: 1,019.60
Molecular Weight: 1,020.208
Elemental Analysis: C, 51.80; H, 7.61; N, 23.34; O, 17.25
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: NOSO-95179; NOSO 95179; NOSO95179;
IUPAC/Chemical Name: (Z)-7-amino-2-((S)-6-amino-2-((S)-2-((S)-1-((2R,8S,11S,14S)-14,18-diamino-11-((S)-2-amino-1-hydroxyethyl)-2-(3-aminopropyl)-8-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazaoctadecanoyl)pyrrolidine-2-carboxamido)-3-(1H-imidazol-5-yl)propanamido)hexanamido)-7-iminohept-2-enoic acid
InChi Key: IIMLLJVGYGUVQJ-JKSAVDOXSA-N
InChi Code: InChI=1S/C44H77N17O11/c1-25(55-42(69)36(33(62)21-48)60-38(65)27(49)10-4-6-16-45)37(64)53-23-35(63)56-29(13-8-18-47)43(70)61-19-9-14-32(61)41(68)59-31(20-26-22-52-24-54-26)40(67)57-28(11-5-7-17-46)39(66)58-30(44(71)72)12-2-3-15-34(50)51/h12,22,24-25,27-29,31-33,36,62H,2-11,13-21,23,45-49H2,1H3,(H3,50,51)(H,52,54)(H,53,64)(H,55,69)(H,56,63)(H,57,67)(H,58,66)(H,59,68)(H,60,65)(H,71,72)/b30-12-/t25-,27-,28-,29+,31-,32-,33-,36-/m0/s1
SMILES Code: N[C@@H](CCCCN)C(N[C@@H]([C@@H](O)CN)C(N[C@@H](C)C(NCC(N[C@H](CCCN)C(N1[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CCCCN)C(N/C(C(O)=O)=C\CCCC(N)=N)=O)=O)=O)CCC1)=O)=O)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 1,020.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Sarciaux M, Pantel L, Midrier C, Serri M, Gerber C, de Figueiredo RM, Campagne
JM, Villain-Guillot P, Gualtieri M, Racine E. Total Synthesis and
Structure-Activity Relationships Study of Odilorhabdins, a New Class of Peptides
Showing Potent Antibacterial Activity. J Med Chem. 2018 Aug 7. doi:
10.1021/acs.jmedchem.8b00790. [Epub ahead of print] PubMed PMID: 30086230