WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H563811
CAS#: 662164-09-2
Description: NCGC00379308, also known as D3-ßArr, is a Positive Allosteric Modulator (PAM) of the TSH receptor. D3-ßArr potentiates the effect of TSH in stimulating β-Arr 1 translocation.
Hodoodo Cat#: H563811
Name: NCGC00379308
CAS#: 662164-09-2
Chemical Formula: C20H23N5
Exact Mass: 333.20
Molecular Weight: 333.439
Elemental Analysis: C, 72.04; H, 6.95; N, 21.00
Synonym: D3-ßArr; D3ßArr; D3 ßArr; NCGC00379308; NCGC-00379308; NCGC 00379308;
IUPAC/Chemical Name: N-(1-Phenylethyl)-2-(1-piperazinyl)-4-quinazolinamine
InChi Key: LOGWGZNWEWFTJV-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H23N5/c1-15(16-7-3-2-4-8-16)22-19-17-9-5-6-10-18(17)23-20(24-19)25-13-11-21-12-14-25/h2-10,15,21H,11-14H2,1H3,(H,22,23,24)
SMILES Code: CC(NC1=C2C=CC=CC2=NC(N3CCNCC3)=N1)C4=CC=CC=C4
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 333.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
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| In vivo protocol: |
